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2025, Vol. 45 No. 11 Published:20 November 2025
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• Qihuang Jianpi Zishen Granules improves renal damage in MRL/lpr mice by inhibiting B cell differentiation via the AIM2/Blimp-1/Bcl-6 axis [ 2297-2308 ]
  Lili CHENG, Zhongfu TANG, Ming LI, Junjie CHEN, Shuangshuang SHANG, Sidi LIU, Chuanbing HUANG

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• Lichong Xiaozheng Granules enhances cisplatin sensitivity of ovarian cancer xenografts in rats by regulating adenine nucleotide translocator 3-mediated mitochondrial apoptosis [ 2309-2319 ]
  Yiliu CHEN, Min MA, Ran SU, Yinbin ZHU, Qing FENG, Jiali LUO, Weifeng FENG, Xianxin YAN

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• circ_EPHB4 synergizes with YTHDF3 to promote glioma progression via m⁶A-dependent stabilization of Wnt3 [ 2320-2329 ]
  Chen JIN, Jingping LIU, Bo LIU, Xiyun FEI, Yuxiang LIAO

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• Molecular mechanism of Xixian Pills for improving rheumatoid arthritis in rats: a proteomic analysis [ 2330-2339 ]
  Yahui LI, Xin YANG, Xueming YAO, Cong HUANG

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• Lycium barbarum polysaccharides alleviates cisplatin-induced granulosa cell injury by downregulating miR-23a [ 2340-2349 ]
  Liuqing LIU, Kun WANG, Xueqing WANG, Bingxin DU

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• Association between Tau protein deposition and brain metabolites: N-acetylaspartate and creatine as potential biomarkers for advanced Alzheimer's disease [ 2350-2357 ]
  Xiaoyuan LI, Yiyue ZHANG, Yucheng GU, Nihong CHEN, Xinyu QIAN, Pengjun ZHANG, Jiaxin HAO, Feng WANG

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• Effect of needle-knife release on the median nerve and transverse carpal ligament in rabbits with carpal tunnel syndrome [ 2358-2364 ]
  Yunnan LI, Qiaoyin ZHOU, Shen LUO, Weilin LIN, Xinyao HUANG, Ying CAO

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• LncRNA Meg3 expression level is negatively correlated with liver fibrosis severity in patients with Wilson disease [ 2365-2374 ]
  Daiping HUA, Qiaoyu XUAN, Lanting SUN, Qingsheng YU, Qin WANG, Tao WANG, Qiyan MA, Wenming YANG, Han WANG

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• Electroacupuncture improves post-traumatic stress disorder in rats by alleviating hippocampal mitochondrial injury via regulating Bcl-2/Bax/caspase-3 signaling [ 2375-2384 ]
  Dandan MA, Jie CHENG, Hong ZHANG, Guang LIU, Kai² SONG

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• Elevated TMCO1 expression in gastric cancer is associated poor prognosis and promotes malignant phenotypes of tumor cells by inhibiting apoptosis [ 2385-2393 ]
  Bowen SONG, Renjie ZHOU, Ying XU, Jinran SHI, Zhizhi ZHANG, Jing LI, Zhijun GENG, Xue SONG, Lian WANG, Yueyue WANG, Lugen ZUO

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• A heterogeneous graph method integrating multi-layer semantics and topological information for improving drug-target interaction prediction [ 2394-2404 ]
  Zihao CHEN, Yanbu GUO, Shengli SONG, Quanming GUO, Dongming ZHOU

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• Reduced intestinal abundance of Gordonibacter increases risk of kidney stones: a Mendelian randomization study and evidence from rat models [ 2405-2415 ]
  Xingxu PAN, Bingqi ZHANG, Zhihua ZHANG, Qiushi CAO

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• High YEATS2 expression promotes epithelial-mesenchymal transition in gastric cancer cells by activating the Wnt/β-catenin signaling pathway [ 2416-2426 ]
  Xuening JIANG, Qingqing HUANG, Ying XU, Shunyin² WANG, Xiaofeng² ZHANG, Lian¹ WANG, Yueyue² WANG, Lugen ZUO

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• Astragaloside IV alleviates D-GAL-induced endothelial cell senescence by promoting mitochondrial autophagy via inhibiting the PINK1/Parkin pathway [ 2427-2437 ]
  Ming YI, Ye LUO, Lu WU, Zeheng WU, Cuiping JIANG, Shiyu CHEN, Xiao KE

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• Qingre Lidan Jiedu Recipe improves high copper load-induced cognitive dysfunction in rats by regulating mitophagy [ 2437-2443 ]
  Yulan WANG, Xiang FANG, Zeming CHEN, Bingkun RUAN, Xinli HAN, Yujie TANG, Luyao ZHU

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• Construction of cardiac organoids derived from human induced pluripotent stem cells for cardiac disease modeling and drug evaluation [ 2444-2455 ]
  Xue GONG, Yongyang FAN, Kaiyuan LUO, Yi YAN, Zhonghao LI

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• Hypaphorine alleviates Crohn's disease-like colitis in mice by inhibiting intestinal epithelial inflammatory response and protecting intestinal barrier function [ 2456-2465 ]
  Qingqing HUANG, Jingjing YANG, Xuening JIANG, Wenjing ZHANG, Yu WANG, Lugen ZUO, Lian WANG, Yueyue WANG, Xiaofeng ZHANG, Xue SONG, Jianguo HU

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• High-throughput circular RNA sequencing reveals tumor-specific high expression of hsa_circ_0001900 in Wilms tumor in association with poor prognosis [ 2466-2474 ]
  Zhiqiang GAO, Jie LIN, Peng HONG, Zaihong HU, Kongkong CUI, Yu WANG, Junjun DONG, Qinlin SHI, Xiaomao TIAN, Guanghui WEI

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• Silencing DDX17 inhibits proliferation and migration of pulmonary arterial smooth muscle cells in vitro by decreasing mTORC1 activity [ 2475-2482 ]
  Xiangxiang DENG, Jia WANG, Mi XIONG, Ting WANG, Yongjian YANG, De LI, Xiongshan SUN

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• Niranthin ameliorates Crohn's disease-like enteritis in mice by inhibiting intestinal epithelial cell apoptosis and protecting intestinal barrier via modulating p38/JNK signaling [ 2483-2495 ]
  Lu TAO, Yue CHEN, Linlin HUANG, Wang ZHENG, Xue SONG, Ping XIANG, Jianguo HU

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• Impact of incorrect designation of working correlation structure matrix on sample size estimation in 2×2 cross design: a simulation study [ 2495-2503 ]
  Peiyu ZHANG, Ziheng XIE, Yan ZHUANG

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• Design and validation of a multimodal model integrating text and imaging data for intelligent assessment of psychological stress in college students [ 2504-2510 ]
  Huirong XIE, Chaobin HU, Guohua LIANG, Hongzhe HAN, Mu HUANG, Qianjin FENG

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• Intubaiton with electromyographic endotracheal tube increases risks of postoperative sore throat following thyroidectomy under general anesthesia: a retrospective cohort study [ 2511-2517 ]
  Lihong CHEN, Yafen CHEN, Huilin XIE, Yancheng HUANG, Yabin HUANG, Sanqing JIN

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• Effect of AI-assisted compressed sensing acceleration on MRI radiomic feature extraction and staging model performance for nasopharyngeal carcinoma [ 2518-2526 ]
  Xinyang LI, Guixiao XU, Jiehong LIU, Yanqiu FENG

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