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2025, Vol. 45 No. 12 Published:20 December 2025
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• Protective effect of Lonicerae Japonicae Flos extract against doxorubicin-induced myocardial injury in mice and the possible mechanisms [ 2527-2540 ]
  Shicheng XIA, Huifang WEI, Weican HONG, Yuming ZHANG, Feiyang YIN, Yixin ZHANG, Linlin ZHANG, Qin GAO, Hongwei YE

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• Morinda officinalis polysaccharide delays osteoarthritis mouse chondrocyte degeneration by modulating the glycolysis-pyroptosis axis via targeting the lncRNA XIST [ 2541-2550 ]
  Changlong FU, Ruolan CHEN, Shiqi XU, Jinxin YOU, Qing LIN, Yanfeng HUANG

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• SERPINE1 overexpression promotes proliferation and paclitaxel resistance of triple-negative breast cancer cells by inducing M2 macrophage polarization [ 2551-2560 ]
  Qian ZHANG, Bowen LIU, Li LEI, Ye WANG, Xinyue ZHANG, Zhangkun MAO, Peng TANG, Jinmei ZHANG, Jiayi YANG, Yanxi PENG, Ze LIU

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• Kahweol improves motor function of mice with spinal cord injury by inhibiting microglial activation via regulating the IκBα/NF-κB pathway [ 2561-2572 ]
  Jinzhi XIA, Yue CHEN, Lü REN, Jing LI, Xue SONG, Lu TAO, Jianguo HU

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• Acupuncture alleviates chronic airway inflammation in obese asthmatic mice by downregulating Vnn1 and FAM126B [ 2573-2584 ]
  Xiaofeng LI, Taochun YE, Lu XI, Chunqiao LI, Huihui LIU

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• Shenqi Xiezhuo Decoction alleviates renal fibrosis in rats by ameliorating oxidative stress and inflammation through the Rap1/MAPK/FoxO3a signaling pathway [ 2585-2597 ]
  Xiaoyu LU, Zhihui LIU, Ye LIU, Tianxiao PANG, Rong BIAN, Ling GUO, Xuehong HE

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• Overwork damages myocardial energy metabolism homeostasis in mice [ 2598-2606 ]
  Junjie CUI, Ruiyin LAI, Suheng CHEN, Shanshan QU, Yue LIAO, Xue MA, Yulan LI

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• Knockdown of Cav1 inhibits mitochondrial function and mRNA m⁶A modification and expression of key genes in mouse hepatocytes [ 2607-2615 ]
  Shanshan DING, Ying LIAO, Xue BAI, Jiaoyang HUANG, Tetsuya ASAKAWA

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• Preoperative serum magnesium as a biomarker for predicting delirium following non-cardiac surgery in elderly patients: a retrospective cohort study [ 2616-2627 ]
  Mengyao YUAN, Xianghan RUAN, Yang LI, Ting ZHANG, Chunxiang HAO, Hao LI, Jingsheng LOU, Jiangbei CAO, Yanhong LIU, Weidong MI, Xiaoying ZHANG

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• Angio-associated migratory cell protein is highly expressed in hepatocellular carcinoma and promotes tumor cell invasion and metastasis [ 2628-2638 ]
  Chao LI, Guozhi YIN, Xiao CHENG, Yezhen JIANG

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• Development and validation of a risk prediction model for cognitive impairment in rural elderly Chinese populations: evidence from the CHARLS study [ 2639-2645 ]
  Fei WANG, Weiran LI, Xiang SHANG, Fei LI

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• Fuzheng Xiaoyan Granules ameliorate cancer-related fatigue during breast cancer chemotherapy by regulating the AKT1/BAD/BCL-2 pathway [ 2646-2657 ]
  Xinyue SUN, Kuanyu WANG, Gang WANG, Qingquan DAI, Jing CHEN, Xiangding KONG, Jia LUAN

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• Dietary secoisolariciresinol diglucoside alleviates chronic kidney disease in offspring rats caused by maternal trans-fatty acid exposure by regulating the Bcl-2/Bax/caspase-3 signaling axis [ 2658-2666 ]
  Siyu MA, Meiqing CHEN, Tianyu WU, Wenhong ZHAO

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• Hugan Decoction alleviates non-alcoholic fatty liver disease in rats by activating the AMPK/m-TOR signaling pathway and reducing lipid synthesis [ 2667-2678 ]
  Du SHANG, Wen LI, Lihua CUI, Ming CHEN

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• Indole-3-acetic acid alleviates Cryptococcus neoformans-induced pyroptosis in cerebral microvascular endothelial cells by regulating stress granule-mediated NLRP3 inflammasome activation [ 2679-2689 ]
  Jingyu CHEN, Jinhu ZOU, Bingliang ZHOU, Xuefeng GAO, Pengwei HUANG, Hong CAO

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• Resveratrol protects barrier function of mouse brain microvascular endothelial cell monolayers with oxygen/glucose deprivation and PM_2.5 exposure by maintaining mitochondrial dynamics balance [ 2690-2698 ]
  Meng QIN, Siyu SUN, Jiaqi LIU, Yujiao GAO, Hao WANG, Youkun WANG, Ao SUN, Jiachun YAN, Jinbao WANG, Ying YU

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• Helicid alleviates depression-like behavior in rats with chronic unpredictable mild stress through the NCALD/sGC/cGMP/PKG axis [ 2699-2707 ]
  Xin DU, Xiaotong ZHANG, Juan LU, Peng GE, Haitao HU, Mengxue FU, Yuanxiang ZHANG, Guodong WANG, Jiucui TONG

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• ResLSTM-TemporalSE: an automated classification model for multi-lead ECG signals [ 2708-2717 ]
  Meng QU, Rong FU

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• Analysis of setup errors and their correlation with clinical factors in image-guided radiotherapy for prostate cancer using different immobilization devices [ 2718-2725 ]
  Xuan GUO, Yang LIU, Yan XIONG, Biaoshui LIU, Ting SONG, Yunfei LI

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• Polyphyllin VII inhibits osteosarcoma xenograft growth in mice by inducing ferroptosis via upregulating SOHLH1 [ 2726-2737 ]
  Danting XIAO, Haijun TANG, Mingxiu YANG, Hongcai TENG, Jiming LIANG, Tianyu XIE, Wenyu FENG, Shangyu LIU, Wei DAI, Hening LI, Yun LIU

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• Human umbilical cord mesenchymal stem cell grafting alleviates inflammatory response in type 1 diabetic mice by suppressing M1 macrophage polarization through Chi3l1 [ 2738-2746 ]
  Xinxin LIU, Yingrui XU, Hongna SHENG, Hao LIU

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• PSMD11 overexpression promotes epithelial-mesenchymal transition in gastric cancer and affects patient prognosis [ 2747-2755 ]
  Renjie ZHOU, Jingjing YANG, Bowen SONG, Xiaohua CHEN, Lian WANG, Yueyue WANG, Lugen ZUO, Bing ZHU

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• Causal relationship between gut microbiota and T cell subsets in the development of colorectal cancer: a Mendelian randomization analysis [ 2756-2766 ]
  Zhenni YU, Jingzhe GAO, Hui SUN, Qin Feng, Xiaoqi NA, Ning ZHANG, Kungshuang SHEN, Yuanyuan WANG, Xijun WANG

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• Evaluation of coronary microvascular dysfunction for assessing prognosis of ST-segment elevation acute myocardial infarction following reperfusion therapy: insights from QFR-AMR [ 2767-2776 ]
  Shiyi GAO, Zichen HAN, Qiang ZENG, Zengwei CHENG, Jun WANG, Pinfang KANG, Hongju WANG, Miaonan LI, Sigan HU

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