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2026, Vol. 46 No. 2 Published:20 February 2026
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• Correlation between cardiovascular health score based on eight life factors and prognosis of ischemic stroke and mediating effect of clinical test indicators: a multicenter prospective cohort study [ 239-246 ]
  Xiaoxiao LIANG, Huilin LUAN, Pengzhen MA, Wenzhu DENG, Jiaxin JIN, Chenyang QUAN, Tingting CHEN, Youcai YANG, Yingzhen XIE

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• Radix codonopsis combined with Poria improves cognitive impairment in rats with unilateral common carotid artery ligation by regulating the ERα/PI3K/Akt signaling pathway [ 247-258 ]
  Jiayao YANG, Yulian He, Yanlei GUO, Fanghong SHANG, Lei HUA, Yong YANG, Xiaomei ZHANG, Jiangping WEI

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• Yiqi Jiedu Formula inhibits proliferation, invasion and migration of nasopharyngeal carcinoma cells by inhibiting the AKT1/GLUT1 signaling pathway [ 259-270 ]
  Hongmiao XU, Lan HE, Yu XIONG, Fang ZOU, Ting LIN, Zhichao JIANG, Le TANG, Yingchun HE, Fangliang ZHOU

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• Lactobacillus plantarum alleviates lead exposure-induced learning and memory impairment in mice by regulating bile acid metabolism and inhibiting hippocampal NLRP3 expression [ 271-277 ]
  Lifan LI, Weijian YU, Meitao TAN, Yunting LI, Anfei LIU, Xiaojing MENG

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• Plasma metabolites mediates the causal effect of inflammatory proteins on Alzheimer's disease: a Mendelian randomization study [ 278-285 ]
  Meimei CHEN, Ruina HUANG, Zhaoyang YANG

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• Total Astragalus saponins reduce astrocyte swelling and AQP4 expression following oxygen-glucose deprivation and reoxygenation by inhibiting the p38 pathway [ 286-292 ]
  Qin YIN, Yuxiao LEI, Xiaoshu WANG, Gang YANG, Zhaohua TANG

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• Huayu Tongbian Decoction promotes efferocytosis of interstitial Cajal cells in rats with slow transit constipation by inhibiting the PI3K/Akt signaling pathway [ 293-300 ]
  Jiahui QIU, Meng CHEN, Ru MAN, Xin CHEN, Dongrui QIU, Qitong CHANG, Hongyu MA

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• Development of an LC-MS/MS method for 32 steroid hormones and exploration of their gestational variations [ 301-315 ]
  Qiqi ZHOU, Junhe CHEN, Chengtao NIE, Qian WANG, Fangbo XIA, Hongwei ZHOU

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• Isovitexin alleviates myocardial oxidative stress injury in diabetic mice by enhancing myocardial SIRT3 expression and reducing oxidative stress [ 316-324 ]
  Yuce PENG, Yi JIANG, Dan MA, An HE, Dingyi LÜ, Minghao LUO, Suxin LUO

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• Curcumin improves osteoporosis in type 2 diabetic mice by inhibiting RANBP3L expression [ 325-334 ]
  Xiaosong ZOU, Xing ZHANG, Ping LI, Ruixue TIAN, Xiaomiao LU

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• Xiezhuo Jiedu Recipe improves ulcerative colitis in rats by regulating Th17/Treg immune balance [ 335-344 ]
  Binjie LI, Xiaofang ZHOU, Xiaomeng LANG, Xin KANG, Jianping LIU

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• Establishment of an Epstein-Barr virus infection model using human nasal organoids [ 345-352 ]
  Jinyan WEI, Hairui ZHENG, Yunteng ZHAO, Yan YU, Yingying XU, Gang LI

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• Dual role of tea consumption in gastrointestinal disease risks: analysis using a risk prediction model integrating interpretable machine learning and large language model [ 353-361 ]
  Junyao CHEN, Zeyu CHEN, Zhaojie LIN, Menghao FANG, Chaoying SHEN, Qi XU, Xiaoyi ZHANG, Lu LU

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• Cajanonic acid A derivative XJ-60 improves liver fibrosis in mice with non-alcoholic fatty liver disease by inhibiting the SP1/TGF-β/Smad3 signaling axis [ 362-373 ]
  Zhaodie GENG, Li HU, Yunli DAI, Ronggang LUO, Tao XU, Xuyang LIAO, Zhiping YUAN, Jianta WANG, Ying XIAO

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• Quercetin inhibits proliferation and migration and promotes apoptosis of gastric cancer cells by promoting phosphorylation-mediated YAP inactivation [ 374-384 ]
  Yuhuang WANG, Wenrui WANG, Shujie CHENG, Yunlong FENG, Zhuo ZHANG, Qiying SHI, Yujia LI, Qianwen HU, Mingcai WU

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• Allergens induce activation of blood CCR3⁺ granulocyte subsets in patients with perennial allergic rhinitis [ 385-393 ]
  Qiuli WANG, Weihua XU, Fangqiu GU, Siqin WANG, Shaoheng HE, Junling WANG

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• High expression of MPP6 predicts poor patient prognosis and promotes malignant biological behaviors of hepatocellular carcinoma cells [ 394-402 ]
  Huihao YU, Yu SHAO, Qianqian CHENG, Xinrui ZHOU, Haiping GENG, Yan YANG

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• Veratric acid relieves oxidative stress and DSS-induced colitis in mice by activating the Nrf2/HO-1 signaling pathway [ 403-411 ]
  Lin YIN, Keni ZHANG, Tong QIAO, Minzhu NIU, Lixia YIN, Xinyue LIU, Zhijun GENG, Jing LI, Jianguo HU

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• Xuebijing Injection in synergy with linezolid alleviates inflammatory injury in mice with MRSA pneumonia by inhibiting the Hla-NLRP3 pathway [ 412-422 ]
  Mengxia YIN, Ruichen LI, Kaibo YANG, Weijie JIAO, Xinguang LIU

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• Verbenalin ameliorates intestinal inflammation and colitis in a mouse model of Crohn's disease by inhibiting the PI3K-AKT pathway [ 423-433 ]
  Linlin HUANG, Wang ZHENG, Jianguo HU, Xue SONG, Lu TAO, Zhijun GENG, Jing LI, Lugen ZUO, Sitang GE

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• cGAS-STING agonist cGAMP enhances natural killer cell-mediated cytotoxicity against gastric cancer cells [ 434-442 ]
  Qiang WANG, Zhixin CHAI, Yulu DENG, Zhiwei ZHANG, Ying GONG, Sheng GAO, Pingfeng FENG

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• Optimized extraction of active components of Paeonia lactiflora and their antioxidant, anti-inflammatory and pigmentation-reducing effects for skin whitening [ 443-455 ]
  Qiao XU, Wenjie LI, Xinyue ZHANG, Yue CHEN, Zitong JIANG, Guangzhe LI, Mingming YAN

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• Drug repositioning prediction based on dynamic feature learning on heterogeneous graphs [ 456-465 ]
  Haokun ZHU, Yanbu GUO, Xiangjun XIN, Chaoyang LI, Dongming ZHOU

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• Comparison of missing data handling methods for AC₁ coefficient estimation [ 466-472 ]
  Keke LI, Lishan XU, Milai YU, Shengli AN

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• Research progress on the correlation between Akkermansia muciniphila and cardiovascular diseases [ 473-478 ]
  Sijie JIANG, Lan GONG, Hua ZHENG

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