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2025, Vol. 45 No.1 Published:20 January 2025
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• High glucose induces pro-inflammatory polarization of macrophages by inhibiting immune-responsive gene 1 expression [ 1-9 ]
  Wei LUO, Yuhang WANG, Yansong LIU, Yuanyuan WANG, Lei AI

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• HDAC1 overexpression inhibits steroid-induced apoptosis of mouse osteocyte-like MLO-Y4 cells by inducing SP1 deacetylation [ 10-17 ]
  Shenyao ZHANG, Min LU, Gaoyan KUANG, Xiaotong XU, Jun FU, Churan ZENG

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• Qingda Granules alleviate brain damage in spontaneously hypertensive rats by modulating the miR-124/STAT3 signaling axis [ 18-26 ]
  Qiaoyan CAI, Yaoyao XU, Yuxing LIN, Haowei LIN, Junpeng ZHENG, Weixiang ZHANG, Chunyu ZHAO, Yupeng LIN, Ling ZHANG

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• Yiqi Yangyin Huazhuo Tongluo Formula alleviates diabetic podocyte injury by regulating miR-21a-5p/FoxO1/PINK1-mediated mitochondrial autophagy [ 27-34 ]
  Kelei GUO, Yingli LI, Chenguang XUAN, Zijun HOU, Songshan YE, Linyun LI, Liping CHEN, Li HAN, Hua BIAN

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• Buyang Huanwu Decoction reduces mitochondrial autophagy in rheumatoid arthritis synovial fibroblasts in hypoxic culture by inhibiting the BNIP3-PI3K/Akt pathway [ 35-42 ]
  Junping ZHAN, Shuo HUANG, Qingliang MENG, Wei FAN, Huimin GU, Jiakang CUI, Huilian WANG

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• Differential expressions of exosomal miRNAs in patients with chronic heart failure and hyperuricemia: diagnostic values of miR-27a-5p and miR-139-3p [ 43-51 ]
  Zhiliang CHEN, Yonggang YANG, Xia HUANG, Yan CHENG, Yuan QU, Qiqi HENG, Yujia FU, Kewei LI, Ning GU

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• Correlation between the Observer's Assessment of Alertness/Sedation score and bispectral index in patients receiving propofol titration during general anesthesia induction [ 52-58 ]
  Lihong CHEN, Huilin XIE, Xia HUANG, Tongfeng LUO, Jing GUO, Chunmeng LIN, Xueyan LIU, Lishuo SHI, Sanqing JIN

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• Value of serum tryptophan in stratified management of 90-day mortality risk in patients with hepatitis B virus-related acute-on-chronic liver failure: a multicenter retrospective study [ 59-64 ]
  Chao ZHOU, Jingjing ZHANG, Qiao TANG, Shuangnan FU, Ning ZHANG, Zhaoyun HE, Jin ZHANG, Tianyi ZHANG, Pengcheng LIU, Man GONG

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• Inhibiting miR-155-5p promotes proliferation of human submandibular gland epithelial cells in primary Sjogren's syndrome by negatively regulating the PI3K/AKT signaling pathway via PIK3R1 [ 65-71 ]
  Yuru ZHANG, Lei WAN, Haoxiang FANG, Fangze LI, Liwen WANG, Kefei LI, Peiwen YAN, Hui JIANG

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• N-acetylneuraminic acid promotes ferroptosis of H9C2 cardiomyocytes with hypoxia/reoxygenation injury by inhibiting the Nrf2 axis [ 72-79 ]
  Chunfei JI, Zongchao ZUO, Jun WANG, Miaonan LI

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• Mechanism of Hedyotis diffusa-Scutellaria barbata D. Don for treatment of primary liver cancer: analysis with network pharmacology, molecular docking and in vitro validation [ 80-89 ]
  Meng XU, Lina CHEN, Jinyu WU, Lili LIU, Mei SHI, Hao ZHOU, Guoliang ZHANG

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• Quercetin mediates the therapeutic effect of Centella asiatica on psoriasis by regulating STAT3 phosphorylation to inhibit the IL-23/IL-17A axis [ 90-99 ]
  Qing LIU, Jing LIU, Yihang ZHENG, Jin LEI, Jianhua HUANG, Siyu LIU, Fang LIU, Qunlong PENG, Yuanfang ZHANG, Junjie WANG, Yujuan LI

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• CXCL12 is a potential therapeutic target for type 2 diabetes mellitus complicated by chronic obstructive pulmonary disease [ 100-109 ]
  Huaiwen XU, Li WENG, Hong XUE

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• Schistosoma japonicum cystatin has protective effects against "two-hit" sepsis in mice by regulating the inflammatory microenvironment [ 110-117 ]
  Wenjuan DUO, Yixiang WANG, Jiaxing WANG, Xinlong XU, Linxian LI, Dongchen YANG, Qili SHEN, Lichun YANG, Xiaojing LIU, Qiwang JING, Liang CHU, Xiaodi YANG

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• NLRP6 overexpression improves nonalcoholic fatty liver disease by promoting lipid oxidation and decomposition in hepatocytes through the AMPK/CPT1A/PGC1A pathway [ 118-125 ]
  Qing SHI, Suye RAN, Lingyu SONG, Hong YANG, Wenjuan WANG, Hanlin LIU, Qi LIU

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• Overexpression of CHMP2B suppresses proliferation of renal clear cell carcinoma cells [ 126-136 ]
  Xiaorui CHEN, Qingzheng WEI, Zongliang ZHANG, Jiangshui YUAN, Weiqing SONG

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• Predictive value of NUF2 for prognosis and immunotherapy responses in pan-cancer [ 137-149 ]
  Yaobin WANG, Liuyan CHEN, Yiling LUO, Jiqing SHEN, Sufang ZHOU

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• Pulsatilla saponin D inhibits invasion and metastasis of triple-negative breast cancer cells through multiple targets and pathways [ 150-161 ]
  Qiao CHU, Xiaona WANG, Jiaying XU, Huilin PENG, Yulin ZHAO, Jing ZHANG, Guoyu LU, Kai WANG

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• A low-dose CT reconstruction method using sub-pixel anisotropic diffusion [ 162-169 ]
  Shizhou TANG, Ruolan SU, Shuting LI, Zhenzhen LAI, Jinhong HUANG, Shanzhou NIU

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• A multi-constraint representation learning model for identification of ovarian cancer with missing laboratory indicators [ 170-178 ]
  Zihan LU, Fangjun HUANG, Guangyao CAI, Jihong LIU, Xin ZHEN

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• PE-CycleGAN network based CBCT-sCT generation for nasopharyngeal carsinoma adaptive radiotherapy [ 179-186 ]
  Yadi HE, Xuanru ZHOU, Jinhui JIN, Ting SONG

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• Quercetin improves heart failure by inhibiting cardiomyocyte apoptosis via suppressing the MAPK signaling pathway [ 187-196 ]
  Xiupeng LONG, Shun TAO, Shen YANG, Suyun LI, Libing RAO, Li LI, Zhe ZHANG

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• A fusion model of manually extracted visual features and deep learning features for rebleeding risk stratification in peptic ulcers [ 197-205 ]
  Peishan ZHOU, Wei YANG, Qingyuan LI, Xiaofang GUO, Rong FU, Side LIU

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• Strategies for long-acting drug design [ 206-212 ]
  Muqi HUANG, Zheng CAI, Shuwen LIU

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