Investigation of cross-infection of Pseudomonas aeruginosa in an intensive care unit

Abstract

Abstract: Objective To investigate the factors responsible for Pseudomonas aeruginosa nosocomial cross-infection in the intensive care unit (ICU) and provide effective measure for the prevention and management.Methods The homology of 7 Pseudomonas aeruginosa strains isolated from the patients in the ICU and the environment was examined by biological, serological, drug-resistance and plasmid analysis.Results The results of serological and plasmid analyses had good consistency, which demonstrated that the 7 Pseudomonas aeruginosa strains originated from solution in the oxygen humidifier, with uniform serological and plasmid type, and belonged to the same clone with cross-infection by contact between the patients or nursing staff and the objects in the ICU.Conclusion Serological and plasmid analyses are more practical for identifying the sources of Pseudomonas aeruginosa cross-infection, which can be prevented by strict disinfection of the instrument and supervision of the nursing staff in the ICU.

CLC Number:

R181.3

LAI Fu-cai¹, BAI Ying-ming², MU Cheng-hui³, PENG Dao-bo¹, ZHAO Hui¹. Investigation of cross-infection of Pseudomonas aeruginosa in an intensive care unit[J]. Journal of Southern Medical University, 2004, 24(11): 1299-1300,1303.

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