To trace the history of TCM, its concept and the evaluate its role in the management of renal stones.

References were retrieved following a thorough bibliographic search using OVID Medline, EMBASE, Cochrane Database. Keywords used included 'traditional chinese medicine', 'urolithiasis', 'calculi', 'herbal medicine', 'kampo', 'kidney'. Relevant review articles, case reports, books were considered along with resources from the Wellcome Trust Collection, Royal Society of Medicine, London.

TCM has been in existence for over 2500 years. It broadly consist of acupuncture, herbal medicine, tuina (massage) and qi gong. The earliest documentation of Chinese herbal medicaments is in the 'Shen Nung Benchau Jing’, believed to be compiled during the Han Dynasty. Historically, it had an extensive role in treatment of chronic diseases, and has been widely used in China and Japan (known as Kampo) for 10 decades, until the introduction of Western medicine in the late 1800s. TCM is popular within urology, including herbal 'ginseng' for the treatment of erectile dysfunction, acupuncture and herbal therapy for overactive bladder and renal stones. In TCM, dysfunction of Qi in the bladder causes damp-heat to diffuse downward and accumulate in the urinary system, over time causing calculus formation. Urolithiasis causing obstruction is believed to block the flow of Qi and therefore result in pain. Haematuria is attributed to the calculus injuries to the meridian. Currently, there is limited but growing evidence based literature on the role TCM in the prevention and treatment of stones. The Chinese State Medicine Administration Bureau issued guidelines in 1994 for management of urolithasis. It categorized it into four syndromes, each with different modes of treatment (Damp heat retention syndrome, qi-stagnation blood stasis syndrome, kidney ying deficiency syndrome and kidney yang deficiency syndrome). Recent evidence showed that medicinal herbs are known to effectively increase the rate of calculus passage, decreased the complications of urolithasis, which indirectly reduces hospitalisation and cost.

From its primitive roots in China, TCM now has a global influence, and we need to recognise the complementary role it plays in urological practice.

TO study multislice CT angiography imaging and post-processing technology of bronchial artery of lung cancer, analyse L1R1 type lung cancer bronchial artery by adopting the technology of MSCTA and image post-processing technology, understand the characteristics of the left and right sides of the bronchial arteries and provide valuable information for embolization treatment of lung cancer by bronchial arterial infusion chemotherapy or perfusion.

A total of 113 cases of type L1R1 lung cancer bronchial artery MSCTA image analysis of detailed observations were collectted. Compared the left and right sides of the bronchial arteries in the open position, opening direction, the difference between the diameter of the opening.

Both side L1R1 type lung cancer of bronchial artery open position, opening direction, opening diameter were significantly different.

Multislice CT angiography imaging and post-processing technology helps to further understand L1R1 type lung cancer bronchial artery anatomical information and promote bronchial arterial infusion chemotherapy or perfusion embolization.

To explore the clinical and MRI characteristic of mass lesion in basal ganglia region.

A total of 52 patients of mass lesion in basal ganglia region received a pathologic diagnosis and MR scan during 2012.1~2015.10. The characteristic of clinical material and MRI were reviewed.

Cystic degeneration was commonly seen in gliomas and germ cell tumors, fat signal was found in germ cell tumors, edema in gliomas were more serious than that in other lesion. Glioblastomas and lymphoma were significantly enhanced.

There is a difference of clinical maerial and MRI between mass lesions in basal ganglia region, which can help differential diagnosis.

To explore the feasibility of Iodixanol 270 mg/mL in hepatic CTA procedure with comparison of the hepatic CTA enhancement, image quality and radiation dose between two scan procedure with different concentration contrast media and tube voltage.

A total of 76 patients (36 men and 40 women) with suspected hepatobiliary disease were underwent hepatic vascular CTA procedure with different contrast media and tube voltage. Patients were divided into 2 groups randomly, 38 in group A received Iopromide 370 mgI/mL at a rate of 5 mL/s with tube voltage of 120 kV, and the remaining 38 patients in group B received Iodixanol 270 mgI/mL at the same flow rate with 100 kV. All the raw data were transferred to an image post-processing workstation for VR, MIP and MPC reconstruction. The CT value, CNR, image quality of the hepatic artery and portal vein were assessed and compared between the groups, also the radiation dose and ADR were compared between the two groups.

There was no statistically difference of CT value, CNR and image quality between 2 groups (P>0.05). The radiation dose of group B (low concentration group) was significant lower than group A. Incidence of injection related discomfort were less than group A.

Low concentration contrast media Iodixanol with low tube voltage scan procedure can be applied in the hepatic vascular CTA.

To observe the differences of the detection of callus in the early healing process after surgery of fractures between Digital Tomosynthesis (DTS) and Digital Rdiography (DR).

A total of 54 patients were performed on DR and DTS imaging after 2 weeks, 1 month, 2 months and 3 months of surgery for fractures and the obtained images were compared.

In 54 patients, the detection rates of callus by DTS and DR were 3.7% and 14.81% respectively at the second week with significant difference (P<0.05), 38.89% and 77.78% after 1 month with significant difference (P<0.05), 66.67% and 87.04% at the 2 months with significant difference(P<0.05), and 88.89% and 94.44% at the 3 months, without significant difference(P>0.05).

DTS has an important value for the early detection of callus after surgery for fractures, which has more obvious advantages over the X-ray plain film.

To investigate the cause of atypical appendicitis ultrasound misdiagnosis and missed diagnosis of influencing factors.

The clinical,anatomy and ultrasonic characteristics of atypical appendicitis with missed diagnosis or misdiagnosis were retrospectively analysed. The effect of the factors on ultrasonic diagnosis of appendicitis were explored by Logistic regression analysis after assignment for dual factors.

Bowel gas, the right lower quadrant abdominal effusion ,retroperitoneal appendix and local echogenicity were the main factor of adult appendicitis with ultrasonic misdiagnosis through 6 step regression analysis. Diverticulitis was a major cause of pediatric appendicitis misdiagnosis (P= 0.000, classification and model of rate of not less than 85%).

The right lower abdomen echogenicity, effusion and intestinal gas interference is a major cause of lead to misdiagnosis and ultrasound misdiagnosis of acute appendicitis. The mesenteric lymphadenitis and Michael diverticulitis should be carefully identified for children with acute lower abdominal pain .

To observe the effect of high intensity focused ultrasound in the treatment of adenomyosis of uterus.

A total of 25 cases of patients with adenomyosis of uterus disease were treated with high intensity focused ultrasound ablation, and were followed up regularly,records of dysmenorrhea and menstrual conditions.

A total of 25 patients completed the treatment and were followed up for 6 months, the remission rate of dysmenorrheal was 86%, menstrual volume reduction rate was 84%,recent curative effect was obvious.

High intensity focused ultrasound ablation is a noninvasive technique to preserve the uterus, recent curative effect is obvious, the long-term effect ie still need to be further clinical observation and verification.

To evaluate the value of prenatal ultrasound in diagnosis of congenital diaphragm hernia.

The ultrasonic data of twenty fetuses with CDH were analyzed retrospectively in this study, the results were compared with postnatal autopsy and operation.

In 20 fetuses with CDH, 19 cases of CDH were detected by prenatal ultrasound diagnosis. Average detection time was 26.1 weeks. 15 located on the left, 4 on the right. 8 cases combined with other malformations. 3 cases of digestive system malformation, 2 cases of urogenital system malformation, 2 cases of cardiovascular system malformation, 1 case of skeletal system malformation. 1 case was missed diagnosis.

Prenatal ultrasound has important clinical value in screening fetal CDH.

To explore the safety and clinical effects of stent embedding under endoscopy by straight sight fordigestive tract stenosis.

Thirty-three patients with digestive tract stenosis admitted to our hospital from 2013 to 2015were selected in this study, including 24 cases of esophagus and cardia, 4 cases of pyloric stenosis and 5 cases of colon stenosis.According to the site and degree of the stenosis, patients were given stent embedding under endoscopy by straight sight.

Among the 33 cases of digestive tract stenosis, except for 2 cases of perforation after stent embedding, 1 case of failureof stent embedding and 2 cases of stent shifting, there were 28 cases(84.8%) of successful stent embedding and the symptomsof digestive tract stenosis were alleviated after stent embedding. Thoracalgia and celialgia occurred in 12 patients anddigestive tract hemorrhage occurred in 4 patients, but these symptoms were mild and disappeared soon with or withoutsymptomatic treatment.

Stent embedding under endoscopy by straight sight has good clinical effects on digestivetract stenosis, but still has some adverse reactions in few patients.

To investigate the correlation between serum-ascites total protein grdient (SATPG) and liver size.

A total of 666 patients with ascites were examined with color doppler ultrasonography. SATPG was examined with abdominalparacentesis, which was the difference of total protein between serum and ascites. Pearson correlation analysis was used toassess the correlation between SATPG and the up-down length of left lobe of liver, the front-back length of left lobe of liver, thethickness of right lobe of liver, portal vein diameter, and portal vein blood flow velocity.

There were no correlationsbetween the levels of SATPG and oblique diameter of right liver , the front-back length of left lobe of liver (r=-0.034, P=0.387; r=?0.048, P=0.219). However, the correlation coefficients between the levels of SATPG and the up-down length of left lobe of liver,the thickness of right lobe of liver, portal vein diameter, and portal vein blood flow velocity were -0.089, -0.082, 0.107and -0.131, respectively (P<0.05).

SATPG can be a good index to reflect the degree of portal pressure, liver size andliver function．

To investigate the safety and feasibility of percutaneous intraductal radiafrequency ablation(RFA) plusbiliary stenting in the treatment of malignant biliary obstruction.

A total of 13 patients with unresectable malignantobstructive jaundice were selected to undergo percutaneus intraductal radiofrequency ablation plus metallic biliary stentplacement. Clinical efficacy was evaluated by observing the operative complications, remission of jaundice, and the stentpatency and survival rate at 1, 3, 6 months were also recorded.

Patients were successfully received the intraductalRFA. No complications such as perforation, biliary leakage or bile peritonitis occurred. Serum total bilirubin was significantlydecreased in 1 week(t=5.156, P<0.01），and the jaundice remission rate was 61.5%. The 1, 3 month patency rate was 100%, the 6month patency rate was 80%（8/10）. The 1 month survival rate was 100%, The 3, 6 month survival rate was 92%（12/13）and 77%（10/13）respectively. Two patients dead of serious drain with advanced tumors in 65,132 days after operation respectively, andone patient dead of disseminated intravascular coagulation in 97 days. Jaundice recurrence occurred in two patients in 4~5months after the procedure were controlled after received the interventional treatment again.

Percutaneousintraductal radiafrequency ablation(RFA) could prolong the malignant biliary obstruction patients' stent patency and life timeeffectively and safely, while its long-term efficacy needs to be further proved.

To investigate the mortality rate of diabetic inpatients and the death-relating factors in a tertiary hospital.

Information of the hospitalized diabetic patients administered at the Department of Endocrinology between 1998and 2009 were retrospectively analyzed. Types of diabetes, hospital days and hospital visits were collected relating to patients’death status.

Among the 59740 diabetic patients, 1283 died, with a mortality rate of 2.1% (2.2% in men and 2.0% inwomen). Average number of hospital visits and hospital days were significantly higher in death group than that in survivalgroup. Mortality rate was 2.8% for the patients with acute complication, 2.4% for the type 2 diabetic patients, and 1.1% forthose with type 1 diabetes.

Types of diabetes, hospital visits and hospital days are death-relating factors inhospitalized diabetic patients.

To observe the influence of neurological intervention combined with dexamethasone injection on theoutcome for the patients suffered from acute ischemic stroke.

Sixty patients with AIS were randomly divided into thedexamethasone group (group A), normal saline group (group B) and the simple intervention group (group C), with 20 cases ineach group. Three groups were compared of postoperative neurological function score (NIHSS) scores, brain tissue relativeapparent diffusion coefficient (rADC), endocrine and complications such as the number of cases.

NIHSS score ofgroup A was lower than that in group B and C (P<0.05) after January; A group was significantly higher than that of group Band C in postoperative day 3 rADC, and the final brain volume was lower than that in group B and C after 1 month; serumcortisol levels between the 3 groups had no significant difference (P>0.05) at postoperative day 1; The postoperativecomplications between the 3 groups of cases constitute had no significant difference (P>0.05).

Nerve involvementwith local use of DXM therapy can relieve cerebral edema and AIS patients reduced cerebral infarction volume, can not affectthe neuroendocrine, does not increase a patient's risk of complications, and help to improve the prognosis of patients with AIS.

To investigate the expression of Fascin in varied endometrial lesions of uterus and to evaluate itsclinicopathological significances in histoloical diagnosis and prognosis prediction of lesions.

Fifty endometrioidadenocarcinomas (EA), 20 atypical hyperplasia of endometrium (AH), 20 endometrial hyperplasia without atypia (HWA) and20 proliferative phase of endometrium (PPE) were collected . Fascin expression was detected in these lesions byimmunohistochemical staining. The relationship between Fascin expression and clinicopathological parameters of lesions wasstatistically analyzed.

There was no expression of Fascin in PPE and HWA and AH showed Fascin expression (15%, 3/20). Fascin could be detected strongly and diffusely in the most of EA (72%, 36/50). There was a significant difference betweenEA and other lesions in Fascin expression (P<0.05). In EAs, Fascin expression was closely correlated with tumor histologicalgrading, FIGO staging, and depth of myometrial invasion, respectively. There was no correlation found between Fascinexpression and lymph node metastasis (P>0.05).

Fascin might be an important molecular marker for differentialdiagnosis between EA and its precursor lesions. Furthermore, Fascin might play a critical role in development and progressionof ES by modulating tumor cell invasion and migration.

To evaluate main risk factors of type 2 diabetes mellitus complicated with coronary heart disease.

A total of 189 patients with type 2 diabetes diagnosed from 2011 to 2012 were selected. The risk factors concurrent forCHD were measured and recorded to make a logistic regression analysis.

With confounding factors ruled out, ORs forCHD in patients with type 2 diabetes were 1.176 (95% CI 1.029~1.343, P=0.017) with body mass index (BMI), 1.173 (95% CI1.010~1.363, P=0.036) with glycated haemoglobin (HbA1C) and 2.646 (95% CI 1.513~4.627, P=0.001) with low-densitylipoprotein cholesterol (LDL-C). Their ORs were 0.103 (95% CI 0.017~0.628, P=0.014) with high-density lipoprotein cholesterol(HDL-C) and 2.812（95% CI 1.637, 4.803, P=0.006）with hypertension. In addition, their ORs for CHD were 1.449 (95% CI 1.097~1.914, P=0.009) with duration of diabetes, 0.438 (95% CI 0.245~0.784, P=0.005) with increased physical activity.

BMI, HbA1C, LDL-c, high blood pressure and diabetic duration are the main risk factors of type 2 diabetes mellituscomplicated with CHD. Increased HDL-c and increased physical activity are protective factors, should be managed.

To research the rational use of medicine to treat hypertension, based on the role of fruits and vegetables intherapy.

220 cases of patients diagnosed with hypertension were randomly divided into two groups. The controlgroup and the treatment group. The control group received conventional western medicine treatment, the treatment groupwere given both the conventional treatment and a reasonable dietary guidance of how to make rational use of fruits andvegetables. Comparing the clinical effects of patients in two groups.

The total effective rate was 91.82% in the controlgroup, at the same time, the other group was 82.73%, There is a significant difference (χ²=4.09, P<0.05). Comparing the effectiverates of two groups by using μ test, and making P<0.05 both two groups, the effect of treatment group is better than the other,after give the different guidance. During Two groups showed no significant adverse reactions.

The therapeuticschedule of making rational use of fruits and vegetables beside using conventional treatment is worth of further study andpromoting, on account of it is high efficacy , affordable, no side effects further.

To analyze the characteristics of cognitive impairment by MOCA in Chaoshan area of elderly populationin different degree of Leukoaraiosis.

A total of 187 cases were collectted with population in different degree ofLeukoaraiosis over the age of 60 in Chaoshan area. The cognitive impairment were assessed by MOCA.

The score ofMOCA was correlated with age, education level, LA level, brain atrophy and hypertension. There was a significant differencein the cognitive function between patients with severe LA and no LA group.

Age, education, LA, brain atrophyand hypertension are risk factors for early cognitive impairment assessment by MOCA. It is negatively correlated with age,LA, brain atrophy, and positively correlated with educational level.The characteristics of the cognitive impairment of LA istype Ⅲ to IV, which can lead to cognitive impairment, affect the visual space , executive function, calculation, language,delayed recall and orientation.

To investigate neonatal asphyxia pulse perfusion index change clinical significance.

A total of 96 cases of full-term newborn asphyxia (asphyxia group), and divided into shock group and non-shock group, and give neonates the appropriate resuscitation and anti-shock therapy according to the specific condition of neonate ; the same period were randomly selected birth 96 cases of full-term newborns as normal control group, open on time after raw milk, breastfeeding on demand. All included studies were recorded in neonates born after 24 hours and 72 hours of pulse perfusion index values.

PI values in Neonates with birth asphyxia group were significantly lower than that in control group. Neonates with shock group after giving birth and 24 hours PI treatment was significantly lower than that in non-shock group, in the comprehensive treatment given to neonates after 72 hours shock group and non-shock group PI values of the two groups showed no significant difference; shock group after comprehensive treatment 24 h, no significant difference when the PI and birth, birth shock group was significantly higher than its value by PI after treatment 72 h; non-shock group of neonates through comprehensive treatment after 24 h and 72 h, which PI values were not statistically significant compared with at birth.

Pulse perfusion index changes can response asphyxia and shock situation of children, to improve the recovery prompt pulse perfusion index of children with the disease.

To investigate the clinical efficacy of lauromacrogol for varicose veins.

During September 2013 to September 2015, 256 cases of patients with varicose veins were randomly divided into two groups. The control group were performed traditional saphenous vein ligation, and the observation group were performed multi-point injection with lauromacrogol foam.

Total effective rate of two treatment methods ware 100%, cure rate of observation group in term 1 was 90.63% (116 cases), cure rate in term 2 was 9.37% (12 cases); the cure rate of traditional group in term 1 was 88.28% (113 cases), cure rate in term 2 was 10.16% (13 cases). Improvement of symptoms were basically the same after treatment, however, lauromacrogol group was significantly better than the control group in surgery length, ambulation time, limb aesthetic level, length of stay and costs. The incidence and severity of complications in lauromacrogol group were much lower than control group (P<0.05).

Multi-point injection with Lauromacrogol foam for varicose veins is simple, effective, minimally invasive and safe with less pain, high compliance and lower rate of complications.

To investigate the value of procalciton guidance for antibiotic application in patients with acute exacerbations of asthma.

Sixty patients with acute exacerbation of asthma which admitted to our hospital were divided into 2 teams according to the randomized, controlled method. Except the similar routine treatment, the control group received antibiotics based on the antibiotic use guide, while the observed group were treated with antibiotics according to PCT levels. Compared the antibiotic utilization rate and duration, hospitalization time, invasive mechanical ventilation rate and fatality rate between the two groups.

Antibiotic utilization rate of the observed group was lower than the control group, and the duration of antibiotic treatment was shorter than the control group, the difference had statistical significance(P< 0.05). PCT had statistical difference（P<0.001）between antibiotics users and non users in the observed group before the treatment, while CRP had no statistically difference (P>0.05). The difference of invasive mechanical ventilation rate and hospitalization time between the two groups had no statistical significance (P>0.05). There was no death case in both groups.

Procalcitonin guidance for antibiotic application in patients with acute exacerbations of asthma can reduce antibiotic utilization rate and shorten the duration of antibiotic.

To study sperm acrosome enzyme activity and sperm parameters in infertile men.

A total of 140 cases of infertile subjects were enrolled and divided into two observation groups by the parameter of acrosome enzyme. Semen parameters included shape and number of semen volume, liquefaction time, appearance, sperm motility. 68 subjects with completely normal semen parameters were selected as observation group 1, while the other 72 subjects in observation group 2 has a history of reproductive system inflammation and at least one abnormal semen parameters, or showed an obvious exception of anti-sperm antibodies (AsAb). Control group was set with 70 cases of normal fertile men. Sperm acrosome activity was analysed by improved Kennedy and compared between these three groups. Sperm samples were all collected by masturbation.

Observation group 2 shows a significantly lower value of male sperm acrosome activity than the other two groups (P<0.05); Sperm concentration of the control group was (136.84±21.77) × 10⁶/mL, higher than the observation group (P<0.05); Acrosome enzyme activity in control group was 92.64±18.75 iIU/10⁶/mL, significantly higher than the observation group 1 (28.79 ± 3.05 iIU/10⁶/mL) and observation group2 (16.47 ± 2.47 iIU/10⁶/mL) (P<0.05).

Reduction of acrosome activity is closely associated with male infertility, Detection of sperm acrosome activity in infertile men , which can fully reflected in the quality of sperm, evaluation of their functional status, is of major clinical value.

To explore the clinical common bacteria to all kinds of antimicrobial resistance.

Drug sensitivitytest were performed by disc diffusion method, the bacterial drug resistance data were analysed through WHONET software.Clinical isolated bacteria resistance data in 2014 wre retrospective analysed.

Drug resistance rate of enterococcusfaecalis to vancomycin, linezolid and teicoplanin for respectively were 1.2%, 1.5% and 0.8%, respectively. Drug resistance rateof enterococcus faecium to vancomycin, linezolid and teicoplanin for respectively was 2.3%, 0.8% and 0.7%,respectively.ESBLs of klebsiella pneumonia detection rate were 36.5%. ESBLs of Escherichia coli detection rate of were 54.7%. The drugresistance rate of Haemophilus influenza to Azithromycin, Ampicillin and Levofloxacin were 4.2% , 35.1% and 2.9% ,respectively. And the drug resistance rate of Haemophilus par influenza to Azithromycin, Ampicillin resistant were 25.6% and36.8%, respectively .

The common bacteria resistance monitored by our hospital for nearly 1 year is similar to theearly stage of the monitoring results. The acinetobacter genera in hydrocarbon alkene drugs have higher resistance. Strictlycontrol the spread of the pandemic strain and take corresponding measures to strengthen the drug resistance surveillance andthe rational.

To investigate the clinical features, diagnosis, therapeutic strategy and prognosis of primary intracranialchoriocarcinoma.

A retrospective review of three rare cases with primary intracranial non-pineal regionchoriocarcinoma diagnosed histopathologically was performed.

One case was intrasellar region choriocacinoma withright cavernous sinus invaded and internal carotid artery wrapped. It was misdiagnosed with nonfunctional pituitaryadenoma preoperatively. Tumor apoplexy was occurred one day before surgery. Panhypopituitarism developed afteremergency opertation. The patient refused to receive any other tumor treatment and died one month later. Tumor of case 2 waslocated in suprasellar region and third ventricle. Serumβ-HCG was 2300 mIU/mL. Radiotherapy and chemotherapy wasperformed after tumor resection. The patient died ten months after being discharged. Case 3 was right basal ganglion lesionwith serum β-HCG 25 mIU/mL on admission. Choriocarcinoma was diagnosed after stereotactic biopsy. The patient wasreceiving chemotherapy and still in follow-up.

Most of the primary intracranial choriocarcinomas are located inpineal region, only extremely rare cases occur in sellar and basal ganglion region. Male predominate in pineal and basalganglion region tumors but female predominate in sellar region tumors. Choriocarcinoma is a highly malignant tumor whichoften progresses rapidly and has poor prognosis. β-HCG is a reliable marker of choriocarcinoma. Recently, chemotherapycombined with operation is the primary treatment for it, and some clinical practices have proved their effect.

To evaluate the role of myringotomy with ventilation tube insertion for otitis media with effusion in thepathogenesis of experimentally induced tympanosclerosis.

Fitty guinea pigs were underwent bilaterallytympanocentesis and inoculated with a suspension of Streptococcus pneumoniae to establish the model of tympanosclerosis.After 7 days, 30 guinea pigs showed evidence of otitis media with effusion and were chosen to preform the followingexperiments. The right ears were treated with myringotomy and inserted with ventilation tube, whereas the left ears wereconducted myringotomy to serve as the control group. Middle ear membranes were obtained at 1, 3 and 6 months after theoperation to observe the morphology changes of tympanic membranes and middle ear mucosa.

The histopathologicalchanges of tympanosclerosis were found in the right ears of the guinea pig models. There was a positive correlation betweenthe duration of ventilation tube insertion and the extent of calcium deposition and fibrosis.

Myringotomy withventilation tube insertion may be involved in the formation of tympanosclerosis. The surgical procedure should be consideredcarefully in clinical scenario.

To analyse the reasons of ALBU EQA unacceptable.

The quality control data were reviewed, the EQC samples stored in -80 ℃ were reran with instruction status checked. Measuring range evaluation of ALBU of turbidimetry and scatteringmetry were performed. The accuracy of turbidimetry and scatteringmetry were ompareed through detected ALBU in 40 clinical samples. ALBU CAP proficiency testing results were analyzed.

The IQC data were in control, rerun data were accordance with reported data, the ALBU measuring range of turbidimetry and scatteringmetry is uniformity, the accuracy of turbidimetry and scatteringmetry detecting ALBU in clinical samples were similar. The evaluation results of CAP proficiency testing were acceptable, the bias between turbidimetry and scatteringmetry detecting ALBU were limited.

ALBU EQC unacceptable will not affect the accuracy of clinical sample results .

To investigate the role of TLR4 in HIBD by observing the change of TLR4 expression and cell apoptosis after hypoxic-ischemic brain damage (HIBD)in a neonatal rat model, and provide an experimental foundation for the futher clinical research.

A total of 80 7day postnatal Sprague-Dawley rats were randomly divided into experimental group (n=40) and control group(n=40). The expression of TLR4 was tested by immunohistochemistry, the apoptotic hippocampus cellswere tested by TUNEL.

The cell apoptosis and the expression of TLR4 increased at HI 6 h, and achieved the hightest increases at HI 12 h, and it continued to maintain the high level in HI 24 h, then decreased at HI 72 h、HI7 d group. There were significant differences of positive rate at different times compared with control group(P<0.05). There was a positive correlation between apoptosis and TLR4(r=0.452) in rats with hypoxic-ischemic brain damage.

TLR4 over expressed in HIBDcan promote cell apoptosis, and play an important role in the pathogenesis of HIBD.

To find out a valid intervention activity for AIDS in community.

Knowledge levels, number and age distribution of community residents from Jan 2012 to Dec2014 were analyzed by using retrospectiv eanalysis.

The correct rate of HIV/AIDS infection routes(sexual contact, blood-borne, and mother to child transmission) was increased up to more than 93%. The rate of HIV/AIDS treated by follow up intervention, CD4 counted, and whose Spouse or sexual partner detected increased significantly. HIV/AIDS were increasely detected, most of them were youn man borned after 1990.

Effective community nursing intervention can improve efficiency of HIV/AIDS control, various AIDS health education activities should be carried out in community in order to control the transmission of AIDS.

To study the patients with allergic rhinitis to standardize dust mite allergen vaccine immune therapy,nursing intervention, strengthening psychological nursing and health education on the immune treatment progress andtreatment effect.

A total of 86 patients with allergic rhinitis were standardized dust mite allergen vaccine immunetherapy, treatment based on the implementation of nursing intervention, strengthening psychological nursing and healtheducation, and the curative effect and symptoms improved ratings, systemic adverse events.

All the 86 patients wereperformed immunotherapy for 2 years, no cases missed. At the end of treatment, 38 cases (44.2%) were markedly effective, 42cases (48.8%) and 6 cases (7%) were ineffective. The total effective rate was 93%.

The effect of immune treatmentfor allergic rhinitis curative is safe, effective and reliable, high quality nursing intervention is the key to ensure the therapeuticeffect.

To observe the effect of the ligation of mucous membrane (RPH) combined with the anal cushion in the treatment of hemorrhoids in the perioperative nursing intervention.

To explored the effect and satisfaction of nursing intervention in the treatment of hemorrhoids by RPH combined with operation. Results Two groups compared, the test group the total efficiency of 99% , satisfaction was 99% , compared with the traditional hemorrhoids surgery, the effect were significant.

Perioperative nursing intervention on postoperative complications of RPH has a significant effect, greatly reducing the recurrence rate and the incidence of complications.