Abstract: Objective To investigate the Clinical safety and effectiveness of propofol medium and long chain fat emulsion
injection for cesarean section. Methods A retrospective analysis was conducted in 88 cesarean section surgeries performed
between January, 2014 and June, 2015 with epidural anesthesia in 44 cases (control) and with total anesthesia with propofol/
long chain fat emulsion injection in 44 cases (observation group). The maternal mean arterial pressure (MAP), SpO2, and heart
rate and neonatal umbilical dynamic venous blood gas analysis (pH, PO2, pCO2) were compared between the two groups.
Results Compared with the control group, heart rate and MAP significantly increased at skin incision in the observation
group. At the other time points, heart rate, MAP, and SpO2 were all comparable between the two groups. The time from skin
incision to newborn delivery was significantly shorter in observation group (P<0.05), but the time from uterine incision to
delivery and neonatal Apgar score were equivalent between the two groups (P>0.05); neonatal umbilical arteriovenous blood
pH, PO2, and pCO2 were all comparable between the two groups. Conclusion Propofol medium and long chain fat emulsion
injection for general anesthesia induction in cesarean section is characterized by rapid metabolism of the anesthetics, rapid
maternal postoperative recovery, and minimal adverse effects on the fetus, and is therefore safe and reliable in clinical use.