Abstract: Precision medicine, based on personalized medicine, is to provide personalized and precise treatment. The
emergence of 3D printing technique as well as genome sequencing provides an effective way to realize precise and
personalized treatment. The application of 3D printing technique in the field of surgery is listed as following: optimize
operation plan to achieve precise and personalized surgery; design personalized navigation template; personalized prosthesis
production; design of personalized tissue and organ. With the development of tissue engineering, new material technology
and genome sequencing and the improvement in related polices and regulations, precision medicine will step on a higher level
in the field of surgery. This review introduces the application of precision medicine in the field of surgery.