Abstract: Objective To compare the image quality of isotropic 3-dimensional fast spin echo (3D-FSE), 3D fast field echo
(3D-FFE), and 2D fast spin echo (2D-FSE) sequences in magnetic resonance imaging (MRI) of the anatomical structure of the
ankle joint. Methods The ankle joints of 10 healthy volunteers were examined with isotropic 3D-FSE, 3D-FFE and 2D-FSE
sequences using a 1.5T MR scanner and 3D reconstruction. The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of
the tissues were measured. Two radiologists evaluated the image quality of the 3 sequences using a 5-point Likert scale in a
double-blinded manner. Results The 3D-FSE sequences resulted in the highest SNRs for all the tissues and the highest CNRs
for differentiation between cartilage and marrow, between muscle and tendon, and between tendon and fluid. In the
estimation of image quality for cartilages, 3D-FFE had the highest score followed by 3D-FSE, and the latter had the highest
score among the 3 sequences in displaying the tendon. Conclusion 3D-FSE sequence has a high performance in displaying the
anatomical structures of complex joints especially for cartilage, ligament, and tendon tissues.