Abstract: Objective To assess the clinical effects of combined endoscopic-laparoscopic technique for one-stage treatment of
cholelithiasis with concomitant choledocholithiasis. Methods A retrospective analysis was conducted of the clinical data of 30
patients (Group A) with cholelithiasis and choledocholithiasis receiving one-stage laparoscopic cholecystectomy (LC)
combined with intraoperative encoscopic retrograde cholangio-pancreatography (ERCP) and 32 patients (Group B) receiving
LC combined with 1aparoscopic common bile duct exploration. The operative time, blood loss, conversion to open surgery
rate, time to postoperative ambulation, calculi residual rate, hospitalization cost and length of hospital stay were analyzed
comparatively. Results There were statistically differences between the two groups in hospitalization cost and length of
hospital stay (P<0.05) but not in the other indices (P>0.05). Conclusion Combined endoscopic-laparoscopic techniques can be a
safe and feasible option for one-stage treatment of concomitant cholelithiasis and choledocholithiasis to allow rapid
postoperative recovery with a shortened hospital stay.