Abstract: Objective To evaluate the effects of sandblasting and different orthodontic adhesives on shear bond strength
between zirconia and enamel. Methods Zirconia ceramic samples were designed and manufactured for 40 extracted human
maxillary first premolars with CAD/CAM system. The samples were randomized into 4 groups for surface treatment with
sandblasting and non-treated with adhesives of 3M Transbond XT or Jingjin dental enamel bonding resin. After 24 h of bonded
fixation, the shear bond strengths were measured by universal mechanical testing machine and analyzed with factorial
variance analysis. Results The shear bond strength was significantly higher in sandblasting group than in untreated group (P<
0.05) and comparable between the two groups with the adhesives of Transbond XT and dental enamel bonding resin (P>0.05).
Conclusion The shear bond strength between zirconia and enamel is sufficient after sandblasting regardless of the application
of either adhesive.