Abstract: Objective To investigate the influence of ozonated water on physical and chemical properties of vacuum sealing
drainage (VSD) materials. Methods VSD materials (foam and sealing membrane) were immersed in 10 μg/ml ozonated water
for 1 h twice daily for 8 days. The foam appearance and microscopic structure of the materials were observed, and tensile tests
and Raman spectrum scan were performed assess the effect of ozonated water. Simulated VSD devices were prepared and
tested for leakproofness under negative pressure after ozonated water treatment. Results Ozonated water treatment for 8 days
caused no obvious abnormal changes in the foam appearance or microscopic structure of the materials. The maximum tensile
load of foam before and after ozonated water treatment was 4.25±0.73 kgf and 2.44±0.19 kgf (P=0.000), the momentary distance
when the foam torn before and after intervention was 92.54 ± 12.83 mm and 64.44 ± 4.60 mm, respectively (P=0.000). The
corresponding results for VSD sealing membrane were 0.70±0.58 kgf and 0.71±0.08 kgf (P=0.698), and 99.30±10.27 mm and
100.95±18.22 mm (P=0.966), respectively. Raman spectroscopy revealed changes in only several wave intensities and no new
chemical groups appeared within the scan range of 400-4000 cm-1. The VSD device was well hermetic after treatment with
ozonated water. Conclusion Except for a decreased stretch resistance property of the foam, VSD materials display no obvious
changes in physical and chemical characteristics after treatment with ozonated water for 8 days.