Journal of Southern Medical University

Journal of Southern Medical University ›› 2006, Vol. 26 ›› Issue (10): 1471-.

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Isolation of the chemical constituents from Shuanghuanglian injection and their structural identification

Lü Ben-qiang1, XING Xue-feng1, LUO Jia-bo1 1Key New Drug Research Lab, College of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China; 2Department of Pharmacy, 421 Hospital of PLA, Guangzhou 510310, China   

  1. 南方医科大学中医药学院中药新药重点实验室； 南方医科大学中医药学院中药新药重点实验室 广东广州510515 中国人民解放军第421医院药剂科； 广东广州510310； 广东广州510515；
  • Online:2006-10-20 Published:2006-10-20

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Abstract: Objective To isolate and identify the chemical constituents of Shuanghuanglian injection. Methods Chromatography and spectral analysis were performed to isolate and identify the chemical constituents respectively. Results and Conclusion Seven compounds were isolated from Shuanghuanglian injection, including chlorogenic acid (Ⅰ), caffeic acid (Ⅱ), chrysophanol (Ⅲ), physcion (Ⅳ), rutin (Ⅴ), baicalein (Ⅵ) and glucose (Ⅶ). The compounds Ⅲ, Ⅳ, Ⅴ and Ⅶ were isolated and identified in Shuanghuanglian injection for the first time. 

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