Abstract: Objective To observe the effect of needling at Baihui(DU20),Shuigou(DU26)and Shenmen(HT7)on glucose metabolism in different regions of the brain in vascular dementia patients.Methods Ten patients with vascular dementia were randomized into 2 groups,and the patients in the control group received the treatment with needling in the routine acupoints for hemiplegia(chosen from 6 Yang meridians of the hand and foot),while those in treatment group received needling at 3 additional acupoints,namely Baihui(DU20),Shuigou(DU26)and Shenmen(HT7),which were specific for dementia treatment.All the patients were examined by positron-emission tomography(PET)to detect the glucose metabolism in different brain regions before and after acupuncture treatment by means of semiquantitative analysis of the average values of radioactive count in the brain regions.Results Needling at the additional 3 acupoints could obviously enhance glucose metabolism in the bilateral frontal lobes,bilateral thalamus,temporal lobe and lentiform nucleus on the uncompromised side.Conclusion The effect of needling at Baihui(DU20),Shuigou(DU26)and Shenmen(HT7)on vascular dementia is closely related to improved cerebral glucose metabolism.