Journal of Southern Medical University

Journal of Southern Medical University ›› 2006, Vol. 26 ›› Issue (04): 456-458.

Previous Articles     Next Articles

A preliminary study of beam weight optimization of intensity-modulated radiation therapy with genetic algorithm

TANG Mu-tao, CHEN Chao-min, ZHOU Ling-hong, LU Qing-wen, WANG Zhuo-yu, CHEN Guang-jie School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China   

  1. 南方医科大学生物医学工程学院； 南方医科大学生物医学工程学院 广东 广州 510515； 广东 广州 510515；
  • Online:2006-04-20 Published:2006-04-20

PDF

1276

Abstract: Objective To study the method for dose calculation and beam weight optimization of intensity-modulated radiation therapy (IMRT). Methods The IMRT dose calculation model based on two-dimensional convolution was constructed, the program of dose calculation and beam weight optimization with geneticalgorithm was written with Visual c#.Net, and the optimization results were analyzed. Results Genetic algorithm optimization of beam weights can produce highly conformal dose distributions within a clinically acceptable computation time. Conclusion Genetic algorithm is valid and efficient in IMRT beam weight optimization, which may facilitate IMRT treatment planning.

CLC Number: