Abstract: Objective To analyze the causes and evaluate the therapies for simple rhinologic headache resulting from rhinal structural abnormalities. Method A retrospective analysis of 62 cases of simple rhinologic headache was conducted. All the patients were examined by high-resolution CT and nasal endoscopy to identify the anatomic structural abnormality in the nasal cavity. After establishment of the diagnosis, the nasal abnormalities were corrected by nasal endoscopic surgery. Result Of all the cases, 46 were cured, 12 responded favorably to the treatment, and 4 failed to respond possibly due to multiple causes of the headache and misdiagnosis. Conclusion High-resolution CT combined with nasal endoscopy may improve the diagnosis of simple rhinologic headache and nasal endoscopic surgery may serve as an effective modality for its treatment by correcting the nasal structural abnormalities.