Factors associated with acute ST-segment elevation myocardial infacrtion with normal angiographic findings of the coronary artery

Abstract

Abstract: Objective To identify the factors related to acute ST-segment elevation myocardial infarction (STEMI) with normal angiographic findings of the coronary artery.Methods An retrospective analysis of the electrocardiographic, echocardiographic, and angiographic data of 271 STEMI cases was conducted. Of these patients, 29 had normal coronary artery by angiography and from the rest patients presenting abnormal angiographic findings of the coronary artery, 60 were randomly selected to serve as the control group. Multiple logistic regression analysis was performed to identify the independent factors related to acute STEMI with normal coronary artery by angiography.Results The incidence rate of STEMI with normal coronary artery was 10.7%. Univariate analysis showed that age, smoking, diabetes mellitus, absence of pre-infarction angina, and wall motion score were related to STEMI with normal coronary artery (P<0.05), whereas multiple logistic regression analysis identified the former 3 factors as the related factors (P<0.05). Wall motion score, left ventricular ejection fraction, cardiac index, and stroke volume index were higher, and cardiac events fewer in patients with normal coronary artery than in those with abnormal coronary artery (P<0.01).Conclusion Acute STEMI with normal coronary artery is more likely to occur in young smokers without pre-infarction angina, possibly in association with spontaneous reperfusion.

CLC Number:

R542.2⁺2

LIANG Zhen-tao¹, GUO Jun², YU Xiao-ping¹, ZHANG Bin¹, ZHANG Wei-xing¹, ZHU Zhong-sheng¹, LUO Hua¹, HUANG Lei¹. Factors associated with acute ST-segment elevation myocardial infacrtion with normal angiographic findings of the coronary artery[J]. Journal of Southern Medical University, 2005, 25(05): 577-579.

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