Journal of Southern Medical University ›› 2005, Vol. 25 ›› Issue (03): 339-341.

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Expression of glucose transporter 1 in the blood-brain barrier around hematoma in rats with cerebral hemorrhage

LI Zhong-qiu, LU Bing-xun, LÜ Tian-ming   

  1. 南方医科大学南方医院神经内科, 广东, 广州, 510515
  • Online:2005-03-20 Published:2005-03-20

Abstract: Objective To observe the expression of glucose transporter 1 (GLUT1 ) in the blood-brain barrier around the hematoma in rats with cerebral hemorrhage.Method Brain tissue around the hematoma in rats with cerebral hemorrhage was prepared for GLUT1 detection by immunohistochemistry.Result The expression of GLUT1 upregulated within 48h after cerebral hemorrhage and downregulated afterwards.Conclusion Protective reaction of the blood-brain barrier can be initiated to ensure glucose supply to the neurons against the injury by cerebral hemorrhage.

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