Expression of macrophage migration inhibition factor in pancreatic carcinoma tissue

Abstract

Abstract: Objective To observe the expression of macrophage migration inhibitory factor (MIF) in pancreatic carcinoma tissue and analyze the relationship between MIF expression and clinical manifestations.Methods MIF expression in pancreatic carcinoma and normal pancreatic tissue were detected with immunohistochemical method.Results The positivity rates of MIF in pancreatic carcinoma and normal pancreatic tissue were 69.4%(25/36) and 0(0/10) respectively. MIF expression was found to relate to the degree of cell differentiation of pancreatic carcinoma, but not to the clinical stages or the status of lymph node metastasis.Conclusion MIF might be related to the pathogenesis of pancreatic carcinoma.

CLC Number:

R322.4

JIN Zhi-qing, ZHI Fa-chao, CHEN Xue-qing, WANG Ya-dong. Expression of macrophage migration inhibition factor in pancreatic carcinoma tissue[J]. Journal of Southern Medical University, 2004, 24(11): 1301-1303.

References

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