Abstract: Objective To assess the safety and therapeutic effect of morcellator in transurethral bipolar plasmakinetic anatomical enucleation (TUPKAEP) of benign prostate hyperplasia (BPH). Methods The clinical data of 47 patients with BPH receiving TUPKAEP between January and July, 2015 were analyzed. During the operation, morcellator was used to smash the enucleated BPH which was aspirated with subatmospheric pressure in 29 cases, and the tissue was smashed with bipolar electrosurgical loop slicing from top to bottom and aspirated by ellic suction in 18 cases. Results The procedures were completed successfully in all the 47 cases. The time used for adenoma dissociation was 2.24±1.09 with morcellator at the speed of 18.43±6.01 g/min, and was 17.19 ± 11.74 min with bipolar electrosurgical loop at the speed of 1.91 ± 0.65 g/min; the mean total operation time was significantly shorter in morcellator group (28.13±14.71 vs 43.22±25.39 min). The 2 groups showed no significant difference in postoperative continuous bladder irrigation time, postoperative indwelling time of urinary catheter or postoperative hospital stay. Conclusions Morcellator is safe and feasible for application in TUPKAEP and helps to shorten the operation time.