Abstract: Objective To assess the value of combined detection of copeptin and ischemia modified albumin (IMA) in early
diagnosis and prognostic evaluation of myocardial damage in patients with acute organic phosphorus pesticide poisoning
(AOPP). Methods A total of 126 AOPP patients were examined for blood copepin and IMA levels and myocardial injury
markers within 1 h after admission. Results Copeptin and IMA levels significantly increased in patients with AOPP compared
with those in the control subjects. Copeptin and IMA levels were significantly higher in severe AOPP cases than in mild to
moderate cases (P<0.05). Logistic regression analysis showed that increased copeptin and IMA levels and severe complications
of AOPP were associated with an increased risk of cardiovascular events. Conclusion Early detection of copeptin and IMA
levels has important clinical value in early diagnosis and prognostic evaluation of myocardial damage in patients with AOPP,
and their levels are positively correlated with the severity of the condition.