Abstract: Objective To investigate the safety and feasibility of domestically made endoscopic stapling instrument in
laparoscopic assisted rectal cancer resection (Dixon). Methods Sixty-four patients with rectal cancer were randomly divided
into the research group (35 cases) to receive laparoscopic assisted rectal cancer resection using ENDO RLC general endoscopic
linear cutter and single-use loading unit and circular staplers with staples (from REACH medical equipment co.LTD) and the
control group (29 cases) to receive surgery with the corresponding products widely used (fom Johnson & Johnson Mdical
Euipment C.Ltd). The clinical data of the two groups were compared. Results Satisfactory therapeutic effects were obtained in
all the cases. The two groups showed no significant differences in the operative time, intraoperative anastomosis success rate,
or postoperative complications (anastomotic bleeding, leakage, or stricture) between the two groups (P>0.05), but the average
cost of endoscopic stapling instrument was significantly lower in the research group (6604.31±699.95 vs 7822.28±576.98 RMB
Yuan, P<0.05). Conclusion The domestic endoscopic stapling instrument is safe, effective and less costly for laparoscopic
assisted rectal cancer resection.