Abstract: Placenta is an important organ to maintain fetal growth, metabolism, maternal and fetal physiologic balance.
Angiogenesis is a critical factor in placental development involved in fetal blood circulation and vascular changes in the
endometrium and placenta. Angiogenesis is closely related to angiogenesis factors such as vascular endothelial growth factor
and placenta growth factor. Fetal growth restriction threats the fetal health in gestation and also increases the long-term
likeliness of several diseases. In this review, the authors summarize the findings in current studies of the relationship between
angiogenesis factors and fetal growth restriction.