Abstract: Objective To develop a method for tumor segmentation on multi-modality magnetic resonance (MR) images based
on parameter optimization of SVM model. Methods Each one of the 4 sub-classifiers was trained using the feature information
in mono-modality MR images and applied to the corresponding modality images. The classification results differed due to
different information in the selected support vectors of the mono-modality images. By modifying the weight values of the
error data points, we chose the best weight values of the sub-classifier to obtain a weighed combination SVM classifier of
multi-modalities for use in MR image segmentation. Result This tumor image segmentation method was validated on the MR
images of brain tumors in 34 patients and resulted in an average classification accuracy of 90.59%. Compared with the 4
mono-modality classifiers, multi-modality RBF kernel SVM classifiers increased the overall accuracy by 5.76%-20.11% .
Conclusion The proposed method combines multi-modality images with SVM classifiers to allow accurate tumor image
segmentation from MR images with a high precision.