Abstract: Objective To investigate the prevalence and risk factors of postpartum depression (PPD) in Tianhe district of
Guangzhou. Methods A total of 1428 postpartum women in 3 hospitals in Tianhe District of Guangzhou were screened with
Edinburg Postnatal Depression Scale (EPDS), Social Support Rating Scale (SSRS) and a self-designed questionnaire of
PPD-related factors during the period from May to September, 2013. Results The prevalence of PPD was 20.03% in these
women. Unconditional logistic regression analysis showed a significant correlation of PPD with education, delivery mode,
only daughter, relationship between mother-in-law and daughter-in-law, newborn gender satisfaction and housing condition
(P<0.05). Multivariate logistic regression analysis identified education, delivery mode, only daughter, relationship between
mother-in-law and daughter-in-law, and newborn gender satisfaction as the risk factors for PPD, and housing condition was
negatively correlated with the incidence of PPD with an OR value of 0.900. Compared with healthy postpartum women, the
patients with PPD exhibited significantly reduced total score of social support rating scale, score of objective support, score of
subjective support, and social utilization degree. Conclusion The prevalence of PPD is high in Tianhe District of Guangzhou,
and health education and psychosocial intervention should be offered to prevent PPD.