Abstract: Objective To compare the dissolution properties of Ginseng micropowder and common powder in vitro and
investigate the effect of micronization on dissolution of Ginseng. Methods Five ginsenosides including Rg1, Re, Rf, Rb1, and
Rb2 were determined by high performance liquid chromatography, and the dissolution curves of Ginseng micropowder and
common powder were drawn. Results The dissolution rates of ginsenosides from micropowder exceeded 90% within 5 min,
significantly greater than that from common powder. But when the powders were packed in tea bags, the dissolution rates of
ginsenosides were higher from common powder than from micropowder. Conclusion Micronization treatments can promote
dissolution of ginsenosides from Ginseng.