Abstract: ObjectiveTo establish an individualized fluid-solid coupled model of intracranial aneurysms based on computed
tomography angiography (CTA) image data. MethodsThe original Dicom format image data from a patient with an
intracranial aneurysm were imported into Mimics software to construct the 3D model. The fluid-solid coupled model was
simulated with ANSYS and CFX software, and the sensitivity of the model was analyzed. The difference between the rigid
model and fluid-solid coupled model was also compared.ResultsThe fluid-solid coupled model of intracranial aneurysm was
established successfully, which allowed direct simulation of the blood flow of the intracranial aneurysm and the deformation
of the solid wall. The pressure field, stress field, and distribution of Von Mises stress and deformation of the aneurysm could
be exported from the model. A small Young’s modulus led to an obvious deformation of the vascular wall, and the walls with
greater thicknesses had smaller deformations. The rigid model and the fluid-solid coupled model showed more differences in
the wall shear stress and blood flow velocity than in pressure. ConclusionThe fluid-solid coupled model more accurately
represents the actual condition of the intracranial aneurysm than the rigid model. The results of numerical simulation with the
model are reliable to study the origin, growth and rupture of the aneurysms.