Abstract: Objective To analyze the clinical characteristics, pathogenesis and management of traumatic interhemispheric subdural hematomas (ISH). Methods Thirty-one traumatic ISH cases were reviewed and analyzed retrospectively. Results Of the 31 patients, 29 were cured and 2 died of multi-system organ failure (MSOF) and cerebral hernia respectively. Typically, ISH manifested hemiplegia or paralysis of the counterlateral lower limb known as falx syndrome. Conclusions CT scans showing hematocele in the interhemispheric subdural space in excess of 20 ml, or with a thickness of hematocele over 1cm, may serve as a diagnostic criteria for ISH. For the treatment of ISH, surgery and conservative management are suggested on the basis of functional disturbance or the stability of the disease.