Blood lipid adsorption of polyethylene glycol/montmorillonite nanocomposite

Abstract

Abstract: Objective To evaluate the effect of polyethylene glycol/montmorillonite (PEG/MMT) nanocomposite material in adsorption of triglyceride (TG), cholesterin and low-density lipoprotein-cholesterol (LDL-C). Methods The structure of PEG/MMT nanocomposite was analyzed by means of X ray diffraction and its effect of blood lipid and albumin adsorption was evaluated in comparison with Na-MMT. Results The interval distance was larger when the PEG of greater molecular weight was used for preparing the nanocomposite, and PEG/MMT nanocomposite had greater adsorption rate of TG, cholesterin and LDL-C in serum than that of serum albumin. MMT material had poor adsorption effect. Conclusion PEG/MMT nanocomposite possesses the potential as a novel adsorbent of blood lipid for clinical use.

CLC Number:

R446

MO Jian-kun¹, QIU Yu-chao², WEI Li-ping², XIE Shao-yu², LAN Meng³, LEI Da¹, XU Geng-ming². Blood lipid adsorption of polyethylene glycol/montmorillonite nanocomposite[J]. Journal of Southern Medical University, 2005, 25(09): 1161-1163.

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