Establishment of canine models of pernetating craniocerebral gunshot wound

Abstract

Abstract: Objective To establish a canine model of pernetating craniocerebral gunshot wound. Method Gunshot wound was induced in 54 cross-bred dogs using 7.62-mm pistol bullets fired using a pistol from a distance of 30 cm in coronal direction with a tilt of 10 degrees toward the orbit, causing pernetating craniocerebral injury 1 cm posterior and 1.5 cm superior to the lateral canthus. The breathing and pathological changes in the brain tissue were observed after the injury. Results Autonomous breathing was recovered in 9 out of 21 dogs with respiratory arrest after the injury, and the total survival rate was 77.8% in the 54 dogs after the injury. Intracranial hematoma, intracranial pneumatosis, contusion and laceration of brain, and cranial bone fragments were found by cranial CT, with the entrance and exit of the bullet seen on the right and left frontal bone respectively. Pathological examination showed contusion and laceration of the brain tissues. Conclusion The model of craniocerebral perforating wound has been successfully established in dogs.

CLC Number:

R651.1

YU Li¹, XU Ru-xiang¹, PENG Ping¹, XIE Pei-zeng², ZHU Hong-sheng², WANG Song-qing². Establishment of canine models of pernetating craniocerebral gunshot wound[J]. Journal of Southern Medical University, 2004, 24(12): 1404-1406.

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