Abstract: Objective To study the etiological factors, perinatal management of prematur e delivery and the outcome of the premature infants.Methods The medical record s of normal deliveries over the past 8 years in our hospital were respectively reviewed to analyze the difference between full-term and premature delivery case s in terms of maternal age, perinatal factors and manner of delivery. The state s of birthing and outcomes of premature were reviewed.Results Preterm premature rupture of the membranes and In vitrofertilization-embryo transfer (IVF-ET) w ere the major causes of premature delivery, which was also related to such fact ors as placenta previa and pregnancy-induced hypertension. Premature delivery wi th unknown causes had been decreasing over these years. The maternal age and hi story of previous birth did not vary significantly between the full-term and th e premature groups, but the later had significantly higher rates of cesarean sec tion, in which 67.64% of the cas-es had Apgar scores≤7. The state of the neonat es and manner of delivery were significantly different between the two groups. In the premature infants, the incidences of hypoxic-anoxic encephalopathy, aspir ation pneumonia and neonatal mortality were significantly higher than those in the full-term infants.Conclusions Rigorous measures for preventing preterm prem ature rup-ture of the membranes and controlling transferred embryo numbers are c rucial to prevent premature delivery. Good perinatal care and exact evaluation of the state of the parturient may also help reduce the incidence of premature d elivery and improve the quality of life of the neonates.