Abstract: Objective To analyze the consistency between cerebral blood flow (CBF) of 3D arterial spin labeling (3D ASL) and dynamic susceptibility contrast perfusion magnetic resonance imaging (DSC-PWI) in the measurement of brain tumors. Methods Nineteen patients with pathologically confirmed brain tumors were enrolled in this study. The brain tumors included glioma (n=9), meningioma (n=5), hemangioblastoma (n=2), cerebral metastasis (n=2) and cavernous hemangioma (n=1). Both ASL and DSC MRI were performed in all the 19 patients (57 regions of interest), and CBF was quantitatively determined. Results A significant consistency was found between CBF measured by 3D ASL and the relative CBF (rCBF) determined by DSC (P=0.005). Conclusion 3D ASL and DSC PWI are consistent in evaluating blood flow in brain tumors and can accurately evaluate brain tumors perfusion.

Key words: magnetic resonance imaging; perfusion; 3D arterial spin labeling; dynamic susceptibility contrast perfusion magnetic resonance imaging; brain tumors