南方医科大学学报 ›› 2015, Vol. 35 ›› Issue (08): 1166-.

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机器人分站式杂交技术治疗冠心病的近期随访

杨明,高长青,刘帅,吴扬,肖苍松,王嵘   

  • 出版日期:2015-08-20 发布日期:2015-08-20

Short-term follow-up results of hybrid coronary revascularization by robotic coronary
artery bypass grafting and stent implantation

  • Online:2015-08-20 Published:2015-08-20

摘要: 目的总结机器人冠状动脉旁路移植与支架植入的杂交手术近期临床结果。方法2007年1月~2013年5月,35例患者接
受器人冠状动脉旁路移植与支架植入的分站式杂交手术。患者的年龄为56.7±9.6岁,其中男性32例,女性3例;冠脉双支病变
10例,三支病变25例,冠脉病变支数2.7±0.5支。首先完成机器人辅助下内乳动脉游离和非体外循环下、内乳动脉到前降支的
吻合,术后2周内行其余病变冠脉的支架植入术,支架植入同期造影检查桥血管的通畅性。术后6个月、1至5年时复查64 排
CT,明确动脉桥血管和支架的通畅性,随访主要心脏不良事件(MACE)包括心源性死亡、急性心肌梗死和靶病变再次血运重建
的发生率。结果所有患者均顺利接受分站式杂交手术,无并发症发生。平均动脉桥血流量为36.0±22.5 mL/min,支架植入时
动脉桥血管造影检查通畅率为100%。35例患者共植入49枚支架,植入1.34±0.6枚,其中23例患者植入支架1枚,11例植入2
枚,1例植入3枚。无失访患者,随访时间6~62(17.5±11.6)月。术后6个月时桥血管和支架内闭塞各1例,但无临床症状,其余患
者桥血管及支架保持通畅,无心绞痛及MACE事件发生。结论机器人冠状动脉旁路移植联合支架植入的分站式杂交有良好的
近期桥血管和支架通畅率,是一种可供选择的治疗多支冠脉病变的微创方案。

Abstract: To assess the short-term outcomes of staged hybrid coronary revascularization performed using robotic-assisted
off-pump coronary bypass grafting followed by percutaneous coronary intervention (PCI) in a non-left anterior descending
(LAD) coronary artery lesion. Methods From January, 2007 to May, 2013, 35 patients (32 male and 3 female patients, mean age
56.7 ± 9.6 years) underwent staged hybrid coronary revascularization. Ten patients had double-vessel and 25 patients had
triple-vessel coronary diseases, and the lesions involved an average of 2.7 ± 0.5 coronary vessels. Coronary artery bypass
grafting was completed in robotic-assisted left internal thoracic artery (ITA) harvesting and LITA to LAD bypass. Coronary
angiography or 64-MSCT was performed to evaluate the patency of the ITA and stents at 6 months and at 1 to 5 years
postoperatively. The patients were followed for major adverse cardiac events (MACE) including cardiac death, acute
myocardial infarction and target lesion revascularization. Results Staged hybrid revascularization was completed successfully
in all the patients without complications. The LITA to LAD anastomosis was completed in minimally invasive direct coronary
bypass grafting (MIDCAB) or totally robotic coronary bypass grafting on beating heart (TECAB) with the assistance of da Vinci
Surgical System. The mean artery graft flow was 36.0±22.5 ml/min, and the graft had a 100% patency before discharge. A total
of 49 stents were deployed in 35 patients within 2 weeks after robotic coronary bypass grafting, with a mean of 1.34±0.6 stents
per case (1 stent in 23 cases, 2 stents in 11 cases, and 3 stents in 1 case). The patients were followed up for 17.5±11.6 months,
and 1 patient had artery graft occlusion and another had in-stent occlusion at 6 months. All the other 33 patients had patent
LITA-to-LAD anastomosis without angina or MACE. Conclusion Staged hybrid revascularization strategy has acceptable
angiographic patency results for both LITA-LAD grafts and PCI interventions.