南方医科大学学报 ›› 2014, Vol. 34 ›› Issue (04): 523-.

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非肿块型钙化性乳腺癌微钙化X线表现与病理结果对照

陈卫国,秦耿耿,徐维敏,廖昕,文婵娟,张玲,欧阳晨雨   

  • 出版日期:2014-04-20 发布日期:2014-04-20

Pathological and mammographic findings of microcalcification in calcified breast
carcinoma without a mass

  • Online:2014-04-20 Published:2014-04-20

摘要: 目的探讨非肿块型钙化性乳腺癌的微钙化X线表现与病理结果的关系,以期提高对不同病理类型非肿块型钙化性乳腺
癌微钙化X线表现的认识。方法收集108例非肿块型钙化性乳腺癌,回顾分析其微钙化形态及分布的X线表现,并与病理结果
进行对照研究。结果微钙化形态、分布在不同病理类型的乳腺癌间差异均无统计学差异(P形态=0.743,P分布=0.389)。微钙化形
态在浸润性与非浸润性癌中的差异亦不具有统计学意义(P=0.382);且浸润性癌与非浸润性癌均以细小多形性钙化多见(分别
约占41.2%、57.5%),而浸润性癌中线样或线样分支状钙化及多种恶性钙化混合较非浸润性多见(32.3% vs 20%)。微钙化分布
在浸润性与非浸润性癌中的差异具有统计学意义(P=0.006),浸润性与非浸润性癌中的微钙化分布分别以段样、成簇分布为主
(分别约占33.8%、45.0%)。结论(1)非肿块型钙化性乳腺癌中不同病理类型间微钙化的形态及分布均不具有鉴别意义。术前
仅根据微钙化特点尚难以鉴别,必须结合其他影像征象及临床资料;(2)术前可依据微钙化形态与分布对浸润性与非浸润性乳
腺癌进行初步鉴别。

Abstract: Objective To explore the correlation between pathological findings and mammographic features of
microcalcification in calcified breast carcinoma without a mass. Methods The morphology and distribution of the
microcalcification lesions displayed by mammography were retrospectively analyzed in 108 cases of the calcified breast
carcinoma without a mass in comparison with the pathological findings of the lesions. Results The mammographic
morphology or distribution of the microcalcification lesions did not differ significantly across different pathological types of
calcified breast carcinoma without a mass (P>0.05). The microcalcification lesions showed no significant morphological
difference between invasive and noninvasive breast carcinomas (P>0.05). Fine pleomorphic calcifications were frequently
found in both invasive and noninvasive breast carcinomas, but fine linear and fine linear branching calcifications and mixed
maglinant calcifications were more common in invasive breast carcinoma. The distribution of the microcalcifications showed
significantly different patterns between invasive and noninvasive breast carcinoma (P=0.006), characterized by segmental and
cluttered distributions of the lesions, respectively. Conclusion There is no specific mammographic features in correlation with
the pathological types of microcalcification lesions in calcified breast carcinoma without a mass, but invasive and noninvasive
calcified breast carcinomas have different mammographic features in the morphology and distribution of the
microcalcifications to allow their preoperative differentiation.