南方医科大学学报 ›› 2013, Vol. 33 ›› Issue (04): 618-.

• • 上一篇    

胰高血糖素瘤诊治1例

成宏,陈茂山,杨光伦   

  • 出版日期:2013-04-20 发布日期:2013-04-20

  • Online:2013-04-20 Published:2013-04-20

摘要: 胰高血糖素瘤是一种临床上罕见的胰岛A细胞肿瘤,以坏死性松懈性游走性红斑、糖尿病、消瘦贫血等为主要表现。本
文报道1例55岁男性,临床症状:体质量下降,贫血貌,全身皮肤大量斑片状红斑,结痂、脱屑、色素沉着等多种形态并存。影像
学检查如CT发现胰腺占位性病变。血清胰高血糖素水平有助于诊断,手术切除为一有效的治疗手段。

Abstract: Glucagonoma is a rare islet alpha-cell tumor. We report a case of glucagonoma in a 55-year-old male patient with
such clinical findings of necrolytic migratory erythema, diabetes mellitus, body weight loss, and anemia. CT examination
found a space-occupying lesion in the pancreas, and an elevated serum glucagon level indicate the diagnosis of glucagonoma,
which was confirmed postoperatively by pathological examination of the tumor tissue. A definite diagnosis of glucagonoma
relies on pathological report, and so far no standard treatment strategy has been available for this tumor. Surgical resection is
an effective means for treatment of glucagonoma.