南方医科大学学报

南方医科大学学报 ›› 2006, Vol. 26 ›› Issue (12): 1749-1752.

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膨体聚四氟乙烯人工心脏瓣膜体外加速疲劳的实验研究

李海波； 王武军； 梁勇； 蔡开灿； 邹小明； 王振康；   

  1. 南方医科大学南方医院胸心外科； 南方医科大学南方医院胸心外科 广东广州510515； 广东广州510515；
  • 出版日期:2006-12-20 发布日期:2006-12-20
  • 基金资助:
    广东省科技计划项目(2002B11703)~~

Accelerated fatigue test in vitro of expanded polytetrafluoroethylene artificial heart valve

LI Hai-bo,WANG Wu-jun,LIANG Yong,CAI Kai-can,ZOU Xiao-ming,WANG Zhen-Kang Department of Cardiothoracic Surgery,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China   

  1. 南方医科大学南方医院胸心外科； 南方医科大学南方医院胸心外科 广东广州510515； 广东广州510515；
  • Online:2006-12-20 Published:2006-12-20

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摘要： 目的测试膨体聚四氟乙烯人工心脏瓣膜(ePTFEAHV)的耐久性。方法以TH-2200型瓣膜体外加速疲劳寿命测试仪对6个ePTFEAHV进行体外加速疲劳实验,总计4亿次。以TH-1200型人工心脏瓣膜体外脉动流试验台测试瓣膜于疲劳实验前后的流体力学参数,并进行对比研究,以测试ePTFEAHV的耐久性。结果疲劳实验前后ePTFEAHV的平均跨瓣压差、有效开口面积无明显改变,返流量及返流率较疲劳实验前减小,差异有统计学意义。结论ePTFEAHV具有良好的耐久性。 更多还原

Abstract: Objective To study the durability of expanded polytetrafluoroethylene artificial heart valve(ePTFE AHV).Methods Six ePTFE AHVs were tested for 400 million times against accelerated fatigue using TH-2200 artificial heart valve exosomatic accelerated fatigue instrument.Hydromechanical parameters of fore-and-aft accelerated fatigue test of the 6 AHVs were obtained by TH-1200 artificial heart valve exosomatic pulsatile stream instrument.Results and Conclusion The mean gradient pressure spanning the valve and the effective orific area of ePTFE AHVs did not undergo significant changes after fore-and-aft the fatigue test,but the regurgitation volume and regurgitation rate of ePTFE AHVs were reduced after the accelerated fatigue test,suggesting good durability of ePTFE AHV.

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