南方医科大学学报 ›› 2006, Vol. 26 ›› Issue (08): 1176-1178.

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强直性脊柱炎临床分期探讨

廖志鹏; 汪青春; 谢秋屏; 田明波;   

  1. 南方医科大学中医药学院; 南方医科大学中医药学院 广东广州510515; 广东广州510515;
  • 出版日期:2006-08-20 发布日期:2006-08-20
  • 基金资助:
    广州市科技局资助课题(2006-z3-E0141)~~

Clinical staging of ankylosing spondylitis

LIAO Zhi-peng, WANG Qing-chun, XIE Qiu-ping, TIAN Ming-bo College of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China   

  1. 南方医科大学中医药学院; 南方医科大学中医药学院 广东广州510515; 广东广州510515;
  • Online:2006-08-20 Published:2006-08-20

摘要: 目的分析强直性脊柱炎患者骶髂关节与脊柱和/或髋关节X线表现严重度之间的相关性,并对其临床分期进行探讨。方法37例确诊的强直性脊柱炎患者均行骶髂关节和受累脊柱和(或)髋关节X线检查,由两名医生对X片各自进行两次盲法阅片评分,对颈椎、腰椎、骶髂关节和髋关节均按BASRI的评分标准进行评分,将结果取平均值后进行统计处理。结果37例患者中脊柱受累Ⅱ级以上30例,占81%,髋关节受累Ⅱ级以上15例,占40.5%。骶髂关节评分与脊柱之间r=0.459;骶髂关节评分与髋关节评分之间r=0.465。结论骶髂关节损害严重度并不能很好的代表脊柱及髋关节损害严重度,按骶髂关节改变来分期难以全面反映病情。

Abstract: Objective To compare the chronic changes between the sacroiliac joints (SIJ) and the spine or the hip joints in conventional radiography of patients with ankylosing spondylitis (AS) and discuss the clinical staging of this disease. Methods All images of the joints of the AS patients were evaluated twice in blinded manner by two doctors. The cervical spine, lumbar spine, sacroiliac joints and hip joints were separately evaluated by BASRI, and the results were averaged and analyzed. Definite involvement was defined as a score ≥2. Results Thirty-seven AS patients (81.0% male with mean age of 28.49 years) were examined, and 81.0% of them had definite involvement of the spine and 40.5% of hip involvement. Pearson product-moment correlation coefficient was 0.459 between BASRI-SIJ and BASRI-s, and 0.465 between BASRI-SIJ and BASRI-h. Conclusion Separately, the severity of SIJ changes can not represent the severity of changes in the spine and hip, etc, therefore SIJ changes may not be sufficient evidence for AS staging. 

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