南方医科大学学报

南方医科大学学报 ›› 2006, Vol. 26 ›› Issue (05): 610-612.

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针刺百会水沟神门影响血管性痴呆患者18FDGPET脑功能成像10例临床分析

陈静； 黄泳； 王升旭； 李求实； 梁永就； 郭勇宁；   

  1. 南方医科大学中医药学院； 千禧颐老院医务室； 星光老人之家二院医务室 广东广州510515； 广东广州510515； 广东广州510407；
  • 出版日期:2006-05-20 发布日期:2006-05-20
  • 基金资助:
    中国博士后科学基金(2004035030)~~

～(18)FDG PET cerebral function imaging in 10 vascular dementia patients receiving needling at Baihui(DU20),Shuigou(DU26) and Shenmen(HT7)

CHEN Jing1,HUANG Yong1,WANG Sheng-xu1,LI Qiu-shi1,LIANG Yong-jiu2,GUO Yong-ning3 1Department of Traditional Chinese Medicine,Southern Medical University,Guangzhou 510515,China;2Medical Department,Millennium Rest home,Guangzhou 510407,China;3Medical Department,Xingguang Rest home,Guangzhou 510407,China   

  1. 南方医科大学中医药学院； 千禧颐老院医务室； 星光老人之家二院医务室 广东广州510515； 广东广州510515； 广东广州510407；
  • Online:2006-05-20 Published:2006-05-20

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摘要： 目的运用正电子发射型计算机断层显像(PET)技术,以18FDG为显影剂,观察针刺百会、水沟、神门对血管性痴呆(VD)患者不同脑区葡萄糖代谢的影响。方法将10例VD病人随机均分为2组。对照组治以针对偏瘫的常规穴位(手足三阳经为主),治疗组加用百会、水沟、神门。治疗前后,所有病人均接受PET检测,框取感兴趣脑区(ROI),将各脑区所得葡萄糖代谢放射性计数采用半定量方式进行治疗前后比较。结果加刺百会、神门、水沟三穴,能显著升高双侧额叶、双侧丘脑、健脑颞叶、健脑豆状核的葡萄糖代谢。结论初步发现百会、水沟、神门治疗VD的机制与其提高脑葡萄糖代谢有关。 

Abstract: Objective To observe the effect of needling at Baihui(DU20),Shuigou(DU26)and Shenmen(HT7)on glucose metabolism in different regions of the brain in vascular dementia patients.Methods Ten patients with vascular dementia were randomized into 2 groups,and the patients in the control group received the treatment with needling in the routine acupoints for hemiplegia(chosen from 6 Yang meridians of the hand and foot),while those in treatment group received needling at 3 additional acupoints,namely Baihui(DU20),Shuigou(DU26)and Shenmen(HT7),which were specific for dementia treatment.All the patients were examined by positron-emission tomography(PET)to detect the glucose metabolism in different brain regions before and after acupuncture treatment by means of semiquantitative analysis of the average values of radioactive count in the brain regions.Results Needling at the additional 3 acupoints could obviously enhance glucose metabolism in the bilateral frontal lobes,bilateral thalamus,temporal lobe and lentiform nucleus on the uncompromised side.Conclusion The effect of needling at Baihui(DU20),Shuigou(DU26)and Shenmen(HT7)on vascular dementia is closely related to improved cerebral glucose metabolism.

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