南方医科大学学报

南方医科大学学报 ›› 2006, Vol. 26 ›› Issue (02): 229-230.

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CT引导经皮氩氦刀靶向治疗软组织肉瘤的临床应用

宋谦； 詹瑛； 李露嘉；   

  1. 解放军第401医院肿瘤科； 青岛大学医学院附属医院； 解放军第401医院肿瘤科 山东青岛266071； 山东青岛266071；
  • 出版日期:2006-02-20 发布日期:2006-02-20

Clinical application of CT-guided percutaneous targeted argon-helium cryoablation for soft tissue sarcoma

SONG Qian, ZHAN Ying, LI Lu-jia Department of Oncology, 401 Hospital of PLA; Affiliated Hospital of Medical College of Qingdao University, Qingdao 266071, China   

  1. 解放军第401医院肿瘤科； 青岛大学医学院附属医院； 解放军第401医院肿瘤科 山东青岛266071； 山东青岛266071；
  • Online:2006-02-20 Published:2006-02-20

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摘要： 目的探讨经皮氩氦刀治疗软组织肉瘤的临床疗效、CT影像学的变化及不良反应。方法 32例软组织肉瘤患者在 CT定位后,经皮穿刺行氩氦刀治疗。结果经氩氦刀治疗后3个月,胸部、腹部、四肢CT复查显示52个肿瘤病灶明显缩小(CR+PR为73．1％)。CT显示肿瘤冷冻后呈低密度坏死区,3个月冷冻区实变,12个月冷冻区阴影几乎消失。术后并发症包括气胸、咳嗽、咯血、腹痛、反应性胸腔积液、转氨酶升高和发热。结论氩氦刀冷冻治疗软组织肉瘤创伤小,效果较好,无严重并发症,是治疗软组织肉瘤的一种新的有效治疗方法。 

Abstract: Objective To evaluate the clinical efficacy of percutaneous targeted argon-helium cryoablation for soft tissue sarcoma and analyze the changes in CT findings and side effects in relation to the treatment. Methods Thirty-two patients with soft tissue sarcoma were treated with CT-guided argon-helium cryoablation. Results Three months after the treatment, 52 tumors showed obvious reduction in size with a total complete and partial remission rate of 73.1%. Postoperative CT scanning displayed low-density local necrosis in the tumors after cryotherapy, and consolidation of the lesions was observed at 3 months and lesion disappearance at 1 year after the therapy. The complications included pneumothorax, coughing, hemoptysis, fever, and slight elevation of aminotransferase. Conclusion CT-guided percutaneous targeted argon-helium cryoablation is safe and effective for lung cancer with minimal invasions. 

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