南方医科大学学报

南方医科大学学报 ›› 2005, Vol. 25 ›› Issue (11): 1435-1437.

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血钙水平与肾癌肿瘤大小、分期的相关性分析

白寒1, 郑少斌1, 吴京2, 刘德忠3   

  1. 1. 南方医科大学南方医院泌尿外科, 广东, 广州, 510515;
    2. 南方医科大学南方医院惠侨科, 广东, 广州, 510515;
    3. 第二炮兵总医院泌尿外科, 北京, 100088
  • 出版日期:2005-11-20 发布日期:2005-11-20
  • 基金资助:
    收稿日期:2005-4-11。
    作者简介:白寒(1967),男,在读博士研究生,副主任医师,主要从事泌尿外科疾病防治工作

Correlation of serum calcium level with tumor size and stage of renal cell carcinoma

BAI Han1, ZHENG Shao-bin1, WU Jing2, LIU De-zhong3   

  1. 1. 南方医科大学南方医院泌尿外科, 广东, 广州, 510515;
    2. 南方医科大学南方医院惠侨科, 广东, 广州, 510515;
    3. 第二炮兵总医院泌尿外科, 北京, 100088
  • Online:2005-11-20 Published:2005-11-20

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摘要： 目的 分析肾细胞癌患者血钙水平和肿瘤大小与分期的相关性,从而进一步发现与病情相关的规律和了解病情。方法 按照血钙水平将肿瘤大小/分期相应地分3组,即降低、正常和升高各3组。利用SPSS10.0软件,对3组不同的肿瘤大小/分期病例进行差异性分析和相关性研究。结果 3组不同的肿瘤大小差异性分析(Kruskal-wallisH)显示,χ2=4.768,df=2,P=0.092;Spearman相关分析显示相关系数为-0.166,P=0.029。3组不同的肿瘤分期差异性分析(Kruskal-WallisH)显示,χ2=4.277,df=2,P=0.118;Spearman相关系数为-0.157,P=0.039。结论 3组不同的肿瘤大小之间差异性无统计学意义,血钙水平与肿瘤大小间存在负相关;3组不同的肿瘤分期之间差异性无统计学意义,血钙水平与肿瘤分期间存在负相关。

Abstract: Objective To analyze the correlation between serum calcium level and tumor size/ stage in patients with renal cell carcinoma (RCC). Methods Totally 173 RCC cases were divided into 3 groups according to their serum calcium level, namely low, normal and high level groups. SPSS10.0 software was used for statistical analysis of the tumor sizes/stages and their association with serum calcium level in the 3 groups. Results and Conclusion Kruskal-Wallis H test revealed no significant difference in the tumor size between the 3 groups (χ2=4.768, df=2, P=0.092), but Spearman correlation analysis suggested inverse correlation between serum calcium and tumor size (r=-0.166, P=0.029). Kruskal-Wallis H test also failed to suggest significant difference in the tumor stage between the 3 groups (χ2=4.277, df=2, P=0.118), but serum calcium was found to beinversely correlated with the tumor stage (r=-0.157, P=0.039 by Spearman correlation analysis)

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