南方医科大学学报

南方医科大学学报 ›› 2005, Vol. 25 ›› Issue (11): 1387-1389.

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高血压患者生存质量评价

陈英1, 王声涌2, 池桂波2, 喻侠华3, 洪城3, 李安荣3   

  1. 1. 广州越秀区第一人民医院心内科, 广东, 广州, 510120;
    2. 暨南大学医学院流行病学教研室, 广东, 广州, 510632;
    3. 广州越秀区第一人民医院, 广东, 广州, 510030
  • 出版日期:2005-11-20 发布日期:2005-11-20
  • 基金资助:
    收稿日期:2005-5-11。
    基金项目:广东省医学科研项目(A2001603);越秀区科技计划项目(越2001-02)
    作者简介:陈英(1965-),女,1993年毕业于暨南大学医学院,硕士,现工作于广东省中医院心电图室,副主任医师,硕士生导师,电话:020-81887233-38202,E-mail:chenyinghy@126.com

Evaluation of quality of life of hypertensive patients

CHEN Ying1, WANG Sheng-yong2, CHI Gui-bo2, YU Xia-hua3, HONG Cheng3, LI An-rong3   

  1. 1. 广州越秀区第一人民医院心内科, 广东, 广州, 510120;
    2. 暨南大学医学院流行病学教研室, 广东, 广州, 510632;
    3. 广州越秀区第一人民医院, 广东, 广州, 510030
  • Online:2005-11-20 Published:2005-11-20

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摘要： 目的 探讨高血压患者生存质量(QOL)。方法 采用世界卫生组织QOL(WHOQOL)-100量表,对319例高血压患者和正常对照人群进行生存质量测量,比较病例组与对照组的生存质量差异。结果 高血压患者生存质量在身体机能、心理状况、独立能力、社会关系、生活环境、个人信仰各领域及QOL-100总评分方面皆显著低于正常对照组人群(P<0.01);调整了其他疾病的混杂作用后,除个人信仰领域外,高血压患者其他各领域及QOL-100总评分方面仍皆低于对照组(P<0.01)。HotellingT2检验及多元方差分析显示,高血压患者与对照组人群的生存质量从6个领域综合来看,具有显著性差异(P<0.01)。结论 在有效降压的同时,积极改善患者的生存质量是临床抗高血压治疗的基本目标。

Abstract: Objective To evaluate the quality of life (QOL) of patients with hypertension. Methods Totally 319 patients with hypertension were investigated for their QOL in comparison with 319 healthy controls using the World Health Organization Quality of Life assessment instrument (WHOQOL-100). Results The scores of physical functions, psychological condition, independent ability, social relation, living environment, and personal faith and the total score of QOL-100 were significantly lower in the hypertensive patients than in the normal subjects (P<0.01). After adjusting the confounding factors of other diseases, the scores of all the items with the exception of personal faith and the total score of QOL-100 were all lower in the patients than in the controls (P<0.01). Hostelling T2 test and multivariate analysis of variance showed significant differences in the QOL between the hypertensive patients and the controls in the 6 domains synthesized (P<0.01), further demonstrating lowered QOL of hypertensive patients in comparison with the healthy population. Conclusion Improvement of the hypertensive patients’ QOL in addition to effective blood pressure control is a basic target in clinical therapy of hypertension.

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