南方医科大学学报 ›› 2005, Vol. 25 ›› Issue (06): 720-722.

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B超下经母腹脐带穿刺术的临床应用

李萍, 范瑞莲, 周沫, 杜娟   

  1. 广东省人民医院/南方医科大学附属华南医院妇产科, 广东, 广州, 510080
  • 出版日期:2005-06-20 发布日期:2005-06-20
  • 基金资助:
    收稿日期:2005-1-26。
    作者简介:李萍(1963- ),女,副主任医师,研究方向:遗传优生与产前诊断,电话:020-83827812-42028,E-mail:liping701@163.com

Clinical application of abdominal cordocentesis under ultrasound guidance

LI Ping, FAN Rui-lian, ZHOU Mo, DU Juan   

  1. 广东省人民医院/南方医科大学附属华南医院妇产科, 广东, 广州, 510080
  • Online:2005-06-20 Published:2005-06-20

摘要: 目的 评价PTC穿刺针在B超引导下行脐带穿刺术的安全性及成功率。方法 对103例有各种产前诊断指征的孕妇在B超引导下行脐带穿刺术。结果 穿刺成功率为98.1%(101/103)。发现染色体异常核型5例,宫内巨细胞病毒(CMV)感染2例,重型α-地中海贫血HbBart’s水肿胎3例。穿刺术后未出现流产、胎死宫内、胎盘早剥、宫内感染等严重并发症。结论 B超引导下经母腹脐带穿刺术是一种成功率高、安全可靠的产前诊断方法。

Abstract: Objective To evaluate the safety and success rate of abdominal cordocentesis using a PTC needle under ultrasound guidance. Methods Cordocentesis was performed under ultrasound guidance in 103 pregnant women with indications of prenatal diagnosis. Results The success rate of cordocentesis was 98.1% (101/103). Abnormal chromosome karyotype was detected in 5, intrauterine cytomegalovirus infection in 2 and alpha-thalassemia major (Hb Barts disease) in 3 cases. Severe complications such as miscarriage, fetal death, placental abruption or intrauterine infection were not found after the operation. Conclusion Abdominal cordocentesis under ultrasound guidance is a safe and reliable approach for prenatal diagnosis.

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