南方医科大学学报

南方医科大学学报 ›› 2005, Vol. 25 ›› Issue (02): 236-238.

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呼吸科住院病人抗菌药物使用及不良反应调查

张庆, 许军, 郑萍, 陈英   

  1. 南方医科大学南方医院药学部, 广东, 广州, 510515
  • 出版日期:2005-02-20 发布日期:2005-02-20
  • 基金资助:
    收稿日期:2004-10-9。
    作者简介:张庆(1973- ),女,江苏南通人,1999年毕业于第一军医大学,硕士,主管药师,电话:020-61641888-87235

Survey of the utilization and adverse effects of antibacterial drugs in patients admitted for respiratory diseases

ZHANG Qing, XU Jun, ZHENG Ping, CHEN Ying   

  1. 南方医科大学南方医院药学部, 广东, 广州, 510515
  • Online:2005-02-20 Published:2005-02-20

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摘要： 目的 评估我院呼吸科住院病人抗菌药物使用情况。方法 回顾呼吸科2002年141份病历,计算抗菌药物利用指数(DUI)和每日抗菌药费,同时调查抗菌药物不良反应。结果 DUI为0.9~1.1者占66.7%,每日抗菌药费为(317.8±194.3)元,有14例抗菌药物不良反应。结论 我院呼吸科抗菌药物使用基本合理,但头孢哌酮-舒巴坦有滥用现象,抗菌药物联合使用不当,药费过高,还需注意抗菌药物对老年人的合理应用。

Abstract: Objective To evaluate the utilization of antibacterial drugs and their adverse effects in patients admitted for respiratory disease based on medical record review. Methods The medical records of 141 inpatients admitted in 2002 for respiratory diseases were reviewed. The drug utilization index(DUI) and daily cost of antibacterial drugs were calculated, with also assessment of the adverse effects in relation to the drug use. Results The DUI ranged from 0.9 to 1.1 in 66.7% of the patients, and the daily cost of the antibacterial drugs was 317.8±194.3 RMB, with a total of 14 cases with adverse drug effects recorded. Conclusions The utilization of antibacterial drugs was basically adequate in Nanfang Hospital though with occasional abuse of cefoperazone and sulbactam, inappropriate combination and high cost of the antibacterial drugs. More careful application of these drugs in old patients is stressed.

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