南方医科大学学报

南方医科大学学报 ›› 2005, Vol. 25 ›› Issue (02): 223-225.

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病毒性脑炎脑血流动力学变化研究

王群1, 夏欣2, 袁惠娟1   

  1. 1. 南方医科大学南方医院神经内科, 广东, 广州, 510515;
    2. 广州空军医院神经内科, 广东广州, 510602
  • 出版日期:2005-02-20 发布日期:2005-02-20
  • 基金资助:
    收稿日期:2004-8-9。
    作者简介:王群(1962- ),女,硕士,副教授、副主任医师,电话:020-61641965,E-mail:zhpn@fimmu.com

Changes of cerebral hemodynamics in patients with virus encephalitis

WANG Qun1, XIA Xin2, YUAN Hui-juan1   

  1. 1. 南方医科大学南方医院神经内科, 广东, 广州, 510515;
    2. 广州空军医院神经内科, 广东广州, 510602
  • Online:2005-02-20 Published:2005-02-20

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摘要： 目的 探讨病毒性脑炎患者脑血流动力学变化及其意义。方法 对38例病毒性脑炎患者和30例对照组进行经颅多普勒超声(TCD)检查。结果 TCD检测显示:正常11例,异常27例,阳性率71%,病毒性脑炎患者急性期大脑中动脉、大脑前动脉、大脑后动脉、椎动脉和基底动脉平均血流速度均明显增快,与恢复期和对照组比较有显著性差异(P<0.001~0.05)。大脑中动脉、大脑后动脉和基底动脉脉动指数均显著升高,与恢复期和对照组比较有显著性差异(P<0.001)。结论 TCD研究结果表明病毒性脑炎,尤其是中、重度患者存在不同程度的脑血管痉挛,部分患者主要表现为脑小动脉痉挛。

Abstract: Objective To explore the changes of cerebral hemodynomics in patients with virus encephalitis(VE). Methods Within the initial 24 h and 21 days after admission, respectively, the patients with acute VE(n=38) suspected to result from viral infections were examined with serial transcranial Doppler ultrasound(TCD) for measurements of the systolic flow velocity(Vs), mean blood velocity(Vm) and the pulsatility index(PI) in the middle, anterior and posterior cerebral arteries(MCA, ACA, PCA) and the basilar artery(BA). Results TCD showed normal findings in 11 and abnormal findings in 27 patients, with a positivity rate of 71%. The Vms were significantly elevated in MCA, ACA, PCA, vertebral artery and BA during the acute phase of VE compared with that of the 30 normal control subjects(P<0.001-0.05). The PIs were significantly increased in MCA, PCA and BA(P<0.001). Conclusion TCD findings indicate the presence of cerebral vasospasm in VE during the acute phase.

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