南方医科大学学报

南方医科大学学报 ›› 2004, Vol. 24 ›› Issue (10): 1212-1214.

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重度卵巢过度刺激综合征的监护和治疗

马明远, 温伟标, 周立新, 誉铁鸥, 方滨   

  1. 佛山市第一人民医院ICU科, 广东, 佛山5, 28000
  • 出版日期:2004-10-20 发布日期:2004-10-20
  • 基金资助:
    收稿日期:2004-3-22。
    作者简介:马明远(1963- ),男,副主任医师,E-mail:mmyuan@fsyyy.com

Intensive care and treatment of severe ovarian hyperstimulation syndrome

MA Ming-yuan, WEN Wei-biao, ZHOU Li-xin, YU Tie-ou, FANG Bin   

  1. 佛山市第一人民医院ICU科, 广东, 佛山5, 28000
  • Online:2004-10-20 Published:2004-10-20

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摘要： 目的 总结重度卵巢过度刺激综合征(OHSS)的临床表现、发病机制及相应的治疗方法。方法 回顾性分析20例重度OHSS的临床资料。结果 重度OHSS发生在超排卵治疗后,临床表现为腹胀、恶心、腹水、胸水、少尿、血液浓缩、水-电解质及酸碱平衡紊乱、氮质血症、血栓形成等。经白蛋白、低分子右旋糖酐、6%贺斯等扩容治疗,腹腔、胸腔穿刺放液,甚至终止妊娠等措施治疗后痊愈。结论 防治重度OHSS的关键在于预防,一旦发生OHSS,需及时、正确地治疗。

Abstract: Objective To investigate the clinical manifestations,pathogenesis and treatment of severe ovarian hyperstimulation syndrome (OHSS).Methods The clinical data of 20 OHSS patients were analyzed retrospectively. Results Severe OHSS occurred after controlled ovarian hyperstimulation for superovulation. The major manifestations of OHSS included abdominal distension,nausea,ascites,hydrothorax,oliguria,concentrated blood, acid-base and electrolytea,disturbance,azotemia,thrombosis etc.,which could be controlled by volume expansion with albumin,low-molecular-weight dextran,6% Haes,abdominal and thoracic drainages or even early pregnancy termination.Conclusion Preventive measure of OHSS is very important,and the patients must be treated timely and correctly once OHSS occurs.

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