南方医科大学学报

南方医科大学学报 ›› 2004, Vol. 24 ›› Issue (10): 1207-1209.

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神经干细胞移植及术后处理:附70例报告

周青1, 张世忠1, 徐如祥1, 徐凯2   

  1. 1. 南方医科大学珠江医院全军神经科学研究所, 广东, 广州, 510282;
    2. 南方医科大学南方医院创伤骨科, 广东, 广州, 510515
  • 出版日期:2004-10-20 发布日期:2004-10-20
  • 基金资助:
    收稿日期:2004-3-20。
    作者简介:周青(1969- ),男,主治医师,在读博士研究生,研究方向为脑损伤和肿瘤的治疗,电话:020-61643262,E-mail:davidzhou2360@hotmail.com

Neural stem cell transplantation and postoperative management: report of 70 cases

ZHOU Qing1, ZHANG Shi-zhong1, XU Ru-xiang1, XU Kai2   

  1. 1. 南方医科大学珠江医院全军神经科学研究所, 广东, 广州, 510282;
    2. 南方医科大学南方医院创伤骨科, 广东, 广州, 510515
  • Online:2004-10-20 Published:2004-10-20

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摘要： 目的 总结脑损伤和脊髓损伤后神经功能障碍病人的神经干细胞移植及术后相关问题的处理经验。方法 对70例脑和脊髓神经干细胞移植病人术后相关问题的处理和恢复情况进行回顾分析。结果 除3例病人出现颅内感染,通过腰穿椎管内给抗生素最终出院外,其余病人术后均顺利出院,而手术后有3例病人性功能完全恢复,5例病人大小便可以自己控制。结论 对于脑损伤功能障碍或者脊髓损伤的截瘫病人,进行脑内或者脊髓神经干细胞移植,对于促进脑功能或者脊髓功能恢复有意义,术后相关问题的处理是手术预后的重要保障。

Abstract: Objective To review the operations of neural stem cells transplantation in patients with brain trauma or spinal cord injury and their postoperative management.Methods A retrospective analysis was conducted in 70 cases of brain trauma or paraplegia treated with neural stem cell transplantation in the recent two years. Results All patients were smoothly discharged except for 3 who developed intracraninal infection corrected with antibiotics via the vertebral canal. Another 3 patients with total loss of sexual function after spinal cord injury for over 1 year recovered sexual function after neural stem cell transplan- tation.Conclusion Neural stem cell transplantation can promote the functional recovery of the brain and spinal cord in patients with brain trauma or spinal cord injury. Proper postoperative management for the patients is crucial to ensure favorable prognosis.

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