犬海水中火器伤后早期血流动力学变化

南方医科大学学报 ›› 2004, Vol. 24 ›› Issue (05): 493-496.

犬海水中火器伤后早期血流动力学变化

孟辉¹, 申洪¹, 刘高望¹, 朱天岭², 张鋆歆¹, 吴正蓉¹, 卜海激¹

1. 第一军医大学病理学教研室;广东, 广州, 51015;
2. 珠海市公安局卫生局, 广东, 珠海, 519000

出版日期:2004-05-20 发布日期:2004-05-20
基金资助:
收稿日期:2003-10-27。
基金项目:全军“十五”医药卫生科研基金资助课题(01MA126)
作者简介:孟辉(1969- ),男,第一军医大学在读博士研究生,主治医师,E-mail:mhgl2008@yahoo.com.cn,mhgl@263.net
通讯作者:申洪,博士研究生导师,电话:020-61648227,Email:hongshen@fimmu.com

Early-stage hemodynamic changes in dogs with gunshot wound in seawater

MENG Hui¹, SHEN Hong¹, LIU Gao-wang¹, ZHU Tian-ling², ZHANG Jun-xin¹, WU Zeng-rong¹, BU Hai-ji¹

1. 第一军医大学病理学教研室;广东, 广州, 51015;
2. 珠海市公安局卫生局, 广东, 珠海, 519000

Online:2004-05-20 Published:2004-05-20

摘要/Abstract

摘要： 目的观察海水中火器伤伤后早期血流动力学变化,为早期救治方案提供科学依据。方法将16只普通级毕格犬分为海水中致伤组(n=14)和地面致伤组(n=2);海水组于海水中枪伤后救出,连续监测早期(53.62±12.19)min血流动力学变化。地面组作为观察对照。结果海水中火器伤后死亡率随头颅、胸、腹、肢体受伤部位不同而呈递减趋势;海水组早期血流动力学的紊乱明显比地面组严重,时间提前15 min。结论海水中火器伤可引起一系列严重的血流动力学变化,对机体的损伤程度较为严重,导致实验犬早期死亡率较高;依据火器伤后早期血流动力学的变化进行临床救治有助于提高早期救治成功率。

Abstract: Objective To investigate the hemodynamic changes in the early stages of gunshot wound of dogs in seawater for exploring early treatment protocol. Method Fourteen conventional Beagles models undergoing gunshot wound in seawater were used along with another 2 dogs receiving the wound on land to serve as control. After the dogs were rescued from the seawater, the respiration (R), heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), central venous pressure (CVP), pulmonary arterial wedge pressure (PAWP), and cardiac output (CO) were measured continuously in the early stages of the wound (53.62±12.19 min following injury), followed by statistical analysis of the results. Results Compared with the control group, the hemodynamic disturbance of the dogs receiving the wound in seawater was relatively severe during the first 15 min of the wound. The mortality tended to descend relevant to the position of the wounds, in the order of the head, chest, abdomen and limbs. Conclusions Gunshot wound in seawater may cause severe hemodynamic changes, resulting in progressive dysfunction of circulation and high mortality rate. Early treatment should be targeted at hemodynamic stabilization in accordance to the characteristic changes during the early stages of the wound.

中图分类号:

孟辉¹, 申洪¹, 刘高望¹, 朱天岭², 张鋆歆¹, 吴正蓉¹, 卜海激¹. 犬海水中火器伤后早期血流动力学变化[J]. 南方医科大学学报, 2004, 24(05): 493-496.

MENG Hui¹, SHEN Hong¹, LIU Gao-wang¹, ZHU Tian-ling², ZHANG Jun-xin¹, WU Zeng-rong¹, BU Hai-ji¹. Early-stage hemodynamic changes in dogs with gunshot wound in seawater[J]. Journal of Southern Medical University, 2004, 24(05): 493-496.

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