南方医科大学学报

南方医科大学学报 ›› 2023, Vol. 43 ›› Issue (12): 2152-2157.doi: 10.12122/j.issn.1673-4254.2023.12.22

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小细胞肺癌术后长期生存病例1例报告及文献回顾

吕纯鑫，朱天仪，樊姗姗，吴秀奇，夏 青   

  1. 上海交通大学医学院附属仁济医院肿瘤科，上海 200127；上海市浦东新区浦南医院肿瘤科，上海 200120；上海交通大学医学院，上海 200025
  • 出版日期:2023-12-20 发布日期:2023-12-29

Small-cell lung carcinoma with long-term survival: a case report and review of the literature

LÜ Chunxin, ZHU Tianyi, FAN Shanshan, WU Xiuqi, XIA Qing   

  1. Department of Oncology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China; Department of Oncology, Punan Hospital of Pudong New District, Shanghai 200120, China; School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, China
  • Online:2023-12-20 Published:2023-12-29

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摘要： 目的 旨在提高对小细胞肺癌异质性的认知，达到个体化诊治的目的，改善小细胞肺癌患者的生存预后。方法 本研究报道由上海交通大学医学院附属仁济医院肿瘤科收治的1例小细胞肺癌长生存病例，分析其临床病理特点、诊疗过程，并结合文献复习，讨论小细胞肺癌的综合治疗策略、异质性及预后。结果 经过综合治疗，本例患者生存时间超13年。结论 小细胞肺癌长期生存病例罕见，应提高对小细胞肺癌异质性的认知，改善小细胞肺癌患者的生存预后。

关键词: 小细胞肺癌；肿瘤异质性；长生存期

Abstract: We report a rare case of small-cell lung carcinoma with long- term survival treated in the Department of Oncology, Renji Hospital, Shanghai Jiao Tong University School of Medicine. The pathological-clinical features and diagnosis-treatment progress were analyzed, and the comprehensive treatment strategies, tumor heterogeneity and prognosis of this tumor type were discussed by comparing with other previous studies. The 62-year-old patient was diagnosed with small-cell lung carcinoma and received surgery, radiotherapy and multi-line treatment, and had survived for 13 years after the surgery. The heterogeneity of small cell lung carcinoma should be carefully evaluated to improve the prognosis of the patients.

Key words: small-cell lung carcinoma; tumor heterogeneity; long-term survival