南方医科大学学报 ›› 2021, Vol. 41 ›› Issue (6): 916-922.doi: 10.12122/j.issn.1673-4254.2021.06.15

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胸部数字合成体层成像时的呼吸信号提取

李 仟,刘 佳,莫 英,于佳弘,张昆鹏,张 华   

  • 出版日期:2021-06-20 发布日期:2021-07-05

Extraction of respiratory signals from chest tomosynthesis

  • Online:2021-06-20 Published:2021-07-05

摘要: 目的 利用一次模型分析在胸部数字合成体层成像(CTS)扫描过程中的扫描对象的呼吸状态。方法 从CTS投影图像中提取横膈肌的运动产生呼吸信号。通过动态规划获取的横膈肌运动轨迹进行模型拟合,根据拟合数据,分离出横膈膜的基底运动曲线及呼吸信号曲线。采用物理体模数据、数字Xcat体模数据和临床患者数据进行实验,验证本文方法的性能。结果 物理体模数据的实验中提取出的横膈膜的运动轨迹是线性的;3组不同类型的呼吸状态下的临床数据实验中都能有效的提取出呼吸信号;Xcat仿真实验中所提取的呼吸信号与原设计的呼吸信号之间的相关系数为0.9797。结论 利用一次模型能够实时地有效获取病人的呼吸运动信息。临床上医生能实时获取病人的呼吸信息,便于医生做出是否要重新扫描的判断。

关键词: 数字合成体层成像;运动分析;呼吸信号

Abstract: Objective To analyze the respiratory motion of the scanned object during acquisition of digital chest tomosynthesis (CTS) using a linear model. Methods Respiratory signals were generated by extracting the motion of the diaphragm from the projection radiographs. The diaphragm trajectory obtained by dynamic programming (DP) was modeled and fitted, and according to the fitting of the data, the base motion curve and respiratory signal curve of the diaphragm were separated. Multipurpose chest phantom data, simulated digital Xcat phantom data and the datasets of 3 clinical patients were used to validate the performance of the proposed method. Results The motion trajectory of the diaphragm extracted from multipurpose chest phantom simulation data was linear. The respiratory signals could be effectively extracted from the 3 datasets of clinical patients in different respiratory states. The correlation coefficient between the respiratory signal extracted in Xcat simulation experiment and the original design was 0.9797. Conclusion The linear model can effectively obtain the respiratory motion information of patients in real time, thus enabling the physicians to make clinical decisions on a rescan.

Key words: chest tomosynthesis; motion analysis; respiratory signals